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GABRB3 产品

(gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))

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This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2010].

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Featured GABRB3 Categories

GABRB3 抗体

High quality antibodies with extensive validation data.

GABRB3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GABRB3 抗体

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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
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Cat. No. ABIN7153497
Quantity 100 μg
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Reactivity Mouse, Rat
Application WB, IHC, ICC
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  • (1)
  • (3)
Cat. No. ABIN1742465
Quantity 100 μL
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Application WB, IHC, IHC (p)
Validations
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Cat. No. ABIN6748502
Quantity 100 μL
Datasheet Datasheet

Recommended GABRB3 蛋白

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Reactivity
Source
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Cat. No.
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Source Wheat germ
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Cat. No. ABIN1354661
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505216
Quantity 100 μg
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Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423804
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GABRB3 Products

Pandya, Palpagama, Turner, Waldvogel, Faull, Kwakowsky: "Sex- and age-related changes in GABA signaling components in the human cortex." in: Biology of sex differences, Vol. 10, Issue 1, pp. 5, (2019) (PubMed).

Palpagama, Sagniez, Kim, Waldvogel, Faull, Kwakowsky: "GABAA Receptors Are Well Preserved in the Hippocampus of Aged Mice." in: eNeuro, Vol. 6, Issue 4, (2019) (PubMed).

Li, Li, Jia, Cao, Wang, Wang, Luo, Zhou, Liu, Mao: "Sodium Valproate Ameliorates Neuronal Apoptosis in a Kainic Acid Model of Epilepsy via Enhancing PKC-Dependent GABAAR γ2 Serine 327 Phosphorylation." in: Neurochemical research, Vol. 43, Issue 12, pp. 2343-2352, (2018) (PubMed).

Brewer, Liu, Buhler, Shirachi, Quock: "Role of spinal GABA receptors in the acute antinociceptive response of mice to hyperbaric oxygen." in: Brain research, Vol. 1699, pp. 107-116, (2018) (PubMed).

Bocker, Heinrich, Liebmann, Hennings, Seemann, Gerth, Jakovcevski, Preobraschenski, Kessels, Westermann, Isbrandt, Jahn, Qualmann, Hübner: "The Na+/H+ Exchanger Nhe1 Modulates Network Excitability via GABA Release." in: Cerebral cortex (New York, N.Y. : 1991), (2018) (PubMed).

Lu, Liu, Jiang, Pan, Ho, Ho: "Effects of Traumatic Stress Induced in the Juvenile Period on the Expression of Gamma-Aminobutyric Acid Receptor Type A Subunits in Adult Rat Brain." in: Neural plasticity, Vol. 2017, pp. 5715816, (2017) (PubMed).

Bohnsack, Carlson, Morrow: "Differential regulation of synaptic and extrasynaptic α4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neurons." in: Neuropharmacology, Vol. 105, pp. 124-32, (2016) (PubMed).

Babateen, Jin, Bhandage, Korol, Westermark, Forsberg Nilsson, Uhrbom, Smits, Birnir: "Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from human glioblastoma." in: European journal of pharmacology, Vol. 748, pp. 101-7, (2015) (PubMed).

He, Duguid, Clark, Panzanelli, Patel, Thomas, Fritschy, Smart: "Interneuron- and GABAA receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells." in: Nature communications, Vol. 6, pp. 7364, (2015) (PubMed).

Nunes, Kuner: "Disinhibition of olfactory bulb granule cells accelerates odour discrimination in mice." in: Nature communications, Vol. 6, pp. 8950, (2015) (PubMed).

Synonyms and alternative names related to GABRB3

gamma-aminobutyric acid type A receptor beta3 subunit (GABRB3), gamma-aminobutyric acid (GABA) A receptor, beta 3 (gabrb3), gamma-aminobutyric acid type A receptor beta 3 subunit (Gabrb3), gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 (Gabrb3), A230092K12Rik, AW049585, beta3, Cp1, eca5, ECA5, Gabrb-3, GABRB3, LOC100230475

Protein level used designations for GABRB3

  • gamma-aminobutyric acid (GABA) A receptor, beta 3
  • gamma-aminobutyric acid receptor subunit beta-3
  • gamma-aminobutyric acid A receptor beta 3
  • gamma-aminobutyric acid receptor subunit beta-3-like
  • GABA-alpha receptor beta-2 subunit
  • GABAA receptor beta-3 subunit
  • GABA(A) receptor subunit beta-3
  • Gamma-aminobutyric acid receptor beta 3
  • gamma-aminobutyric acid (GABA-A) receptor, subunit beta 3
  • gamma-aminobutyric acid receptor, subunit beta 3
  • testis gamma-aminobutyric acid receptor subunit beta 3
  • GABA-A receptor beta-3 subunit
  • cleft palate 1
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