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GABRA6 产品

(gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

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GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008].

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Featured GABRA6 Categories

GABRA6 抗体

High quality antibodies with extensive validation data.

GABRA6 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GABRA6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, ICC, IF
Validations
  • (2)
Cat. No. ABIN6258813
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3180636
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN228348
Quantity 100 μL
Datasheet Datasheet

Recommended GABRA6 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354656
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2565095
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421914
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GABRA6 Products

Sona Khan, Trenet, Xing, Sibley, Abbas, Al-Rashida, Rauf, Mandyam: "A Novel Sulfonamide, 4-FS, Reduces Ethanol Drinking and Physical Withdrawal Associated With Ethanol Dependence." in: International journal of molecular sciences, Vol. 21, Issue 12, (2020) (PubMed).

Takashima, Fannon, Galinato, Steiner, An, Zemljic-Harpf, Somkuwar, Head, Mandyam: "Neuroadaptations in the dentate gyrus following contextual cued reinstatement of methamphetamine seeking." in: Brain structure & function, Vol. 223, Issue 5, pp. 2197-2211, (2019) (PubMed).

Fan, Lai, Hor, Lee, Huang, Sieghart, Ernst, Knutson, Cook, Chiou: "The α6 subunit-containing GABAA receptor: A novel drug target for inhibition of trigeminal activation." in: Neuropharmacology, Vol. 140, pp. 1-13, (2018) (PubMed).

Joensuu, Tegelberg, Reinmaa, Segerstråle, Hakala, Pehkonen, Korpi, Tyynelä, Taira, Hovatta, Kopra, Lehesjoki: "Gene expression alterations in the cerebellum and granule neurons of Cstb(-/-) mouse are associated with early synaptic changes and inflammation." in: PLoS ONE, Vol. 9, Issue 2, pp. e89321, (2014) (PubMed).

Green, Grozeva, Moskvina, Hamshere, Jones, Jones, Forty, Caesar, Gordon-Smith, Fraser, Russell, St Clair, Young, Ferrier, Farmer, McGuffin, Holmans, Owen, ODonovan, Craddock: "Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 7, pp. 1347-9, (2010) (PubMed).

Herden, Pardo, Hajela, Yuan, Atchison: "Differential effects of methylmercury on gamma-aminobutyric acid type A receptor currents in rat cerebellar granule and cerebral cortical neurons in culture." in: The Journal of pharmacology and experimental therapeutics, Vol. 324, Issue 2, pp. 517-28, (2008) (PubMed).

Krook-Magnuson, Li, Paluszkiewicz, Huntsman: "Tonically active inhibition selectively controls feedforward circuits in mouse barrel cortex." in: Journal of neurophysiology, Vol. 100, Issue 2, pp. 932-44, (2008) (PubMed).

Pöltl, Hauer, Fuchs, Tretter, Sieghart: "Subunit composition and quantitative importance of GABA(A) receptor subtypes in the cerebellum of mouse and rat." in: Journal of neurochemistry, Vol. 87, Issue 6, pp. 1444-55, (2004) (PubMed).

Sen, Villafuerte, Nesse, Stoltenberg, Hopcian, Gleiberman, Weder, Burmeister: "Serotonin transporter and GABAA alpha 6 receptor variants are associated with neuroticism." in: Biological psychiatry, Vol. 55, Issue 3, pp. 244-9, (2004) (PubMed).

Ogris, Pöltl, Hauer, Ernst, Oberto, Wulff, Höger, Wisden, Sieghart: "Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit." in: Biochemical pharmacology, Vol. 68, Issue 8, pp. 1621-9, (2004) (PubMed).

Synonyms and alternative names related to GABRA6

gamma-aminobutyric acid type A receptor alpha 6 subunit (Gabra6), gamma-aminobutyric acid type A receptor alpha6 subunit (GABRA6), gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6 (Gabra6), gamma-aminobutyric acid (GABA) A receptor, alpha 6a (gabra6a), alpha6, Gabra-6, GABRA6, LOC100224835, si:dkey-217k23.1, zgc:73148

Protein level used designations for GABRA6

  • GABA(A) receptor subunit alpha-6
  • GABA-A receptor alpha-6 subunit
  • gamma-aminobutyric acid A receptor, alpha 6
  • gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6
  • gamma-aminobutyric acid A receptor, alpha 6
  • gamma-aminobutyric acid receptor subunit alpha-6
  • GABA subunit A receptor alpha 6
  • GABA(A) receptor, alpha 6
  • gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • gamma-aminobutyric acid receptor subunit alpha-6-like
  • GABA-ARalpha6
  • gamma-aminobutyric acid A recptor, subunit alpha 6
  • subunit alpha 6 gamma-aminobutyric acid (GABA-A) receptor
  • GABA-A receptor a6 subunit
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