GABRA5 产品
(gamma-aminobutyric Acid (GABA) A Receptor, alpha 5 (GABRA5))
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GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008].
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Featured GABRA5 Categories
Recommended GABRA5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA
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- (2)
Cat. No.
ABIN7153488
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7127506
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IHC, ICC
Validations
- (3)
Cat. No.
ABIN1742462
Quantity
50 μg
Datasheet
Datasheet
Recommended GABRA5 蛋白
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Reactivity
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Reactivity
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Wheat germ
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Cat. No.
ABIN1354652
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7421713
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2712290
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our GABRA5 Products
: "Histone Deacetylase Inhibitor Suberanilohydroxamic Acid Treatment Reverses Hyposensitivity to γ-Aminobutyric Acid in the Ventral Tegmental Area During Ethanol Withdrawal." in: Alcoholism, clinical and experimental research, (2018) (PubMed).: "Effects of Traumatic Stress Induced in the Juvenile Period on the Expression of Gamma-Aminobutyric Acid Receptor Type A Subunits in Adult Rat Brain." in: Neural plasticity, Vol. 2017, pp. 5715816, (2017) (PubMed).
: "Regulating anxiety with extrasynaptic inhibition." in: Nature neuroscience, Vol. 18, Issue 10, pp. 1493-500, (2015) (PubMed).
: "Mice lacking Gad2 show altered behavioral effects of ethanol, flurazepam and gabaxadol." in: Addiction biology, Vol. 15, Issue 1, pp. 45-61, (2009) (PubMed).
: "Functional role of GABAergic innervation of the cochlea: phenotypic analysis of mice lacking GABA(A) receptor subunits alpha 1, alpha 2, alpha 5, alpha 6, beta 2, beta 3, or delta." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 40, pp. 10315-26, (2006) (PubMed).
: "Imidazenil and diazepam increase locomotor activity in mice exposed to protracted social isolation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 11, pp. 4275-80, (2006) (PubMed).
: "Subunit composition and quantitative importance of GABA(A) receptor subtypes in the cerebellum of mouse and rat." in: Journal of neurochemistry, Vol. 87, Issue 6, pp. 1444-55, (2004) (PubMed).
: "Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit." in: Biochemical pharmacology, Vol. 68, Issue 8, pp. 1621-9, (2004) (PubMed).
: "A-kinase anchoring protein 79/150 facilitates the phosphorylation of GABA(A) receptors by cAMP-dependent protein kinase via selective interaction with receptor beta subunits." in: Molecular and cellular neurosciences, Vol. 22, Issue 1, pp. 87-97, (2003) (PubMed).
: "Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype." in: Nature neuroscience, Vol. 3, Issue 6, pp. 587-92, (2000) (PubMed).
Synonyms and alternative names related to GABRA5
gamma-aminobutyric acid type A receptor alpha5 subunit (GABRA5), gamma-aminobutyric acid (GABA) A receptor, alpha 5 (gabra5), gamma-aminobutyric acid type A receptor alpha 5 subunit (Gabra5), gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5 (Gabra5), gamma-aminobutyric acid receptor subunit alpha-5 (LOC100653497), A230018I05Rik, GABRA5, si:dkey-93p24.1Protein level used designations for GABRA5
- gamma-aminobutyric acid (GABA) A receptor, alpha 5
- gamma-aminobutyric acid A receptor, alpha 5-like
- gamma-aminobutyric acid receptor subunit alpha-5-like
- GABA(A) receptor subunit alpha-5
- GABA-A receptor alpha-5 subunit
- gamma-aminobutyric acid A receptor, alpha 5
- gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5
- gamma-aminobutyric acid A receptor, alpha 5
- gamma-aminobutyric acid receptor subunit alpha-5
- GABAA receptor alpha5 subunit
- ligand-gated ion channel subunit
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