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GABRA2 产品

(gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured GABRA2 Categories

GABRA2 抗体

High quality antibodies with extensive validation data.

GABRA2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

GABRA2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GABRA2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN1387528
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, ICC, IF
Validations
  • (3)
Cat. No. ABIN6261858
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN3022576
Quantity 100 μL
Datasheet Datasheet

Recommended GABRA2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966946
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6966947
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956035
Quantity 96 tests
Datasheet Datasheet

Recommended GABRA2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398773
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408378
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1330100
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our GABRA2 Products

Mulligan, Abreo, Neuner, Parks, Watkins, Houseal, Shapaker, Hook, Tan, Wang, Ingels, Peng, Lu, Kaczorowski, Bryant, Homanics, Williams et al.: "Identification of a Functional Non-coding Variant in the GABA A Receptor α2 Subunit of the C57BL/6J Mouse Reference Genome: Major Implications for Neuroscience ..." in: Frontiers in genetics, Vol. 10, pp. 188, (2019) (PubMed).

Lu, Liu, Jiang, Pan, Ho, Ho: "Effects of Traumatic Stress Induced in the Juvenile Period on the Expression of Gamma-Aminobutyric Acid Receptor Type A Subunits in Adult Rat Brain." in: Neural plasticity, Vol. 2017, pp. 5715816, (2017) (PubMed).

Ardi, Albrecht, Richter-Levin, Saha, Richter-Levin: "Behavioral profiling as a translational approach in an animal model of posttraumatic stress disorder." in: Neurobiology of disease, Vol. 88, pp. 139-47, (2016) (PubMed).

Wefelmeyer, Cattaert, Burrone: "Activity-dependent mismatch between axo-axonic synapses and the axon initial segment controls neuronal output." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 31, pp. 9757-62, (2015) (PubMed).

Zhao, Sakagami, Suzuki: "Detergent-dependent separation of postsynaptic density, membrane rafts and other subsynaptic structures from the synaptic plasma membrane of rat forebrain." in: Journal of neurochemistry, Vol. 131, Issue 2, pp. 147-62, (2015) (PubMed).

Herrera-Molina, Sarto-Jackson, Montenegro-Venegas, Heine, Smalla, Seidenbecher, Beesley, Gundelfinger, Montag: "Structure of excitatory synapses and GABAA receptor localization at inhibitory synapses are regulated by neuroplastin-65." in: The Journal of biological chemistry, Vol. 289, Issue 13, pp. 8973-88, (2014) (PubMed).

Ohkawa, Satake, Yokoi, Miyazaki, Ohshita, Sobue, Takashima, Watanabe, Fukata, Fukata: "Identification and characterization of GABA(A) receptor autoantibodies in autoimmune encephalitis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 24, pp. 8151-63, (2014) (PubMed).

Kitayama, Morita, Sultana, Kikushige, Mgita, Ueno, Hirata, Kanematsu: "Phospholipase C-related but catalytically inactive protein modulates pain behavior in a neuropathic pain model in mice." in: Molecular pain, Vol. 9, pp. 23, (2013) (PubMed).

Werner, Swihart, Rau, Jia, Borghese, McCracken, Iyer, Fanselow, Oh, Sonner, Eger, Harrison, Harris, Homanics: "Inhaled anesthetic responses of recombinant receptors and knockin mice harboring α2(S270H/L277A) GABA(A) receptor subunits that are resistant to isoflurane." in: The Journal of pharmacology and experimental therapeutics, Vol. 336, Issue 1, pp. 134-44, (2010) (PubMed).

Tian, Chen, Cross, Edenberg: "Alternative splicing and promoter use in the human GABRA2 gene." in: Brain research. Molecular brain research, Vol. 137, Issue 1-2, pp. 174-83, (2005) (PubMed).

Synonyms and alternative names related to GABRA2

gamma-aminobutyric acid type A receptor alpha2 subunit (GABRA2), gamma-aminobutyric acid type A receptor alpha1 subunit (GABRA1), gamma-aminobutyric acid (GABA) A receptor, alpha 2 (gabra2), gamma-aminobutyric acid type A receptor alpha2 subunit (Gabra2), gamma-aminobutyric acid (GABA) A receptor, alpha 2 S homeolog (gabra2.S), gamma-aminobutyric acid (GABA) A receptor, alpha 2 (GABRA2), gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 (Gabra2), C630048P16Rik, Gabra-2

Protein level used designations for GABRA2

  • GABA(A) receptor subunit alpha-2
  • gamma-aminobutyric acid receptor subunit alpha-2
  • GABA-A receptor alpha-1 subunit
  • gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • gamma-aminobutyric acid A receptor alpha 2
  • gamma-aminobutyric acid A receptor, alpha 2 precursor-like
  • GABA(A) receptor, alpha 2
  • gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2
  • gamma-aminobutyric acid receptor A2 subunit
  • gamma-aminobutyric acid A receptor, alpha 2
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