GABRA1 产品
(gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
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This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
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Recommended GABRA1 抗体
Product
Reactivity
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Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, ICC, IF
Validations
- (4)
Cat. No.
ABIN2485717
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, ICC, IF, AA
Validations
- (4)
Cat. No.
ABIN863138
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, ICC, IF
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Cat. No.
ABIN2485730
Quantity
100 μg
Datasheet
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Recommended GABRA1 ELISA试剂盒
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Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6228560
Quantity
96 tests
Datasheet
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Recommended GABRA1 蛋白
Latest Publications for our GABRA1 Products
: "Corticotropin-Releasing Factor Receptor-1 Neurons in the Lateral Amygdala Display Selective Sensitivity to Acute and Chronic Ethanol Exposure." in: eNeuro, Vol. 7, Issue 2, (2020) (PubMed).: "Strain-specific programming of prenatal ethanol exposure across generations." in: Alcohol (Fayetteville, N.Y.), Vol. 60, pp. 191-199, (2017) (PubMed).
: "α2 Subunit-Containing GABAA Receptor Subtypes Are Upregulated and Contribute to Alcohol-Induced Functional Plasticity in the Rat Hippocampus." in: Molecular pharmacology, Vol. 92, Issue 2, pp. 101-112, (2017) (PubMed).
: "How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs." in: Neuron, Vol. 91, Issue 4, pp. 792-807, (2016) (PubMed).
: "Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9526-39, (2016) (PubMed).
: "Role of microRNA-4458 in patients with non-small-cell lung cancer." in: Oncology letters, Vol. 12, Issue 5, pp. 3958-3966, (2016) (PubMed).
: "The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration." in: Nature neuroscience, Vol. 18, Issue 7, pp. 988-96, (2015) (PubMed).
: "The developmental evolution of the seizure phenotype and cortical inhibition in mouse models of juvenile myoclonic epilepsy." in: Neurobiology of disease, Vol. 82, pp. 164-175, (2015) (PubMed).
: "GABAergic interneuronal loss and reduced inhibitory synaptic transmission in the hippocampal CA1 region after mild traumatic brain injury." in: Experimental neurology, Vol. 273, pp. 11-23, (2015) (PubMed).
: "Seizure-related regulation of GABAA receptors in spontaneously epileptic rats." in: Neurobiology of disease, Vol. 77, pp. 246-56, (2015) (PubMed).
Synonyms and alternative names related to GABRA1
gamma-aminobutyric acid type A receptor alpha1 subunit (GABRA1), gamma-aminobutyric acid type A receptor alpha1 subunit (Gabra1), gamma-aminobutyric acid (GABA) A receptor, alpha 1 (gabra1), gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1), gamma-aminobutyric acid receptor subunit alpha-1 (LOC100653509), ECA4, EJM, EJM5, Gabra-1, zgc:153566Protein level used designations for GABRA1
- GABA(A) receptor subunit alpha-1
- GABA(A) receptor, alpha 1
- gamma-aminobutyric acid receptor subunit alpha-1
- gamma-aminobutyric acid A receptor, alpha 1
- gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1
- gamma-aminobutyric acid A receptor, alpha 1
- gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
- GABAA alpha 1
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