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GABRA1 产品

(gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))

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This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].

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Featured GABRA1 Categories

GABRA1 抗体

High quality antibodies with extensive validation data.

GABRA1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GABRA1 抗体

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Cat. No. ABIN2485717
Quantity 100 μg
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Cat. No. ABIN863138
Quantity 100 μg
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Cat. No. ABIN2485730
Quantity 100 μg
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Recommended GABRA1 ELISA试剂盒

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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6228560
Quantity 96 tests
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Recommended GABRA1 蛋白

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Source Wheat germ
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Cat. No. ABIN1354645
Quantity 10 μg
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Cat. No. ABIN7123050
Quantity 50 μg
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Latest Publications for our GABRA1 Products

Agoglia, Zhu, Ying, Sidhu, Natividad, Wolfe, Buczynski, Contet, Parsons, Roberto, Herman: "Corticotropin-Releasing Factor Receptor-1 Neurons in the Lateral Amygdala Display Selective Sensitivity to Acute and Chronic Ethanol Exposure." in: eNeuro, Vol. 7, Issue 2, (2020) (PubMed).

Popoola, Nizhnikov, Cameron: "Strain-specific programming of prenatal ethanol exposure across generations." in: Alcohol (Fayetteville, N.Y.), Vol. 60, pp. 191-199, (2017) (PubMed).

Lindemeyer, Shen, Yazdani, Shao, Spigelman, Davies, Olsen, Liang: "α2 Subunit-Containing GABAA Receptor Subtypes Are Upregulated and Contribute to Alcohol-Induced Functional Plasticity in the Rat Hippocampus." in: Molecular pharmacology, Vol. 92, Issue 2, pp. 101-112, (2017) (PubMed).

Acuna, Liu, Südhof: "How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs." in: Neuron, Vol. 91, Issue 4, pp. 792-807, (2016) (PubMed).

Di, Wang, Han, Fu, Duerfeldt, Blagg, Mu: "Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9526-39, (2016) (PubMed).

Bao, Wang, Wei, Wang, Wuyun, Bo: "Role of microRNA-4458 in patients with non-small-cell lung cancer." in: Oncology letters, Vol. 12, Issue 5, pp. 3958-3966, (2016) (PubMed).

Kang, Shen, Zhou, Xu, Macdonald: "The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration." in: Nature neuroscience, Vol. 18, Issue 7, pp. 988-96, (2015) (PubMed).

Arain, Zhou, Ding, Zaidi, Gallagher: "The developmental evolution of the seizure phenotype and cortical inhibition in mouse models of juvenile myoclonic epilepsy." in: Neurobiology of disease, Vol. 82, pp. 164-175, (2015) (PubMed).

Almeida-Suhett, Prager, Pidoplichko, Figueiredo, Marini, Li, Eiden, Braga: "GABAergic interneuronal loss and reduced inhibitory synaptic transmission in the hippocampal CA1 region after mild traumatic brain injury." in: Experimental neurology, Vol. 273, pp. 11-23, (2015) (PubMed).

González, Grabenstatter, Cea-Del Rio, Cruz Del Angel, Carlsen, Laoprasert, White, Huntsman, Brooks-Kayal: "Seizure-related regulation of GABAA receptors in spontaneously epileptic rats." in: Neurobiology of disease, Vol. 77, pp. 246-56, (2015) (PubMed).

Synonyms and alternative names related to GABRA1

gamma-aminobutyric acid type A receptor alpha1 subunit (GABRA1), gamma-aminobutyric acid type A receptor alpha1 subunit (Gabra1), gamma-aminobutyric acid (GABA) A receptor, alpha 1 (gabra1), gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1), gamma-aminobutyric acid receptor subunit alpha-1 (LOC100653509), ECA4, EJM, EJM5, Gabra-1, zgc:153566

Protein level used designations for GABRA1

  • GABA(A) receptor subunit alpha-1
  • GABA(A) receptor, alpha 1
  • gamma-aminobutyric acid receptor subunit alpha-1
  • gamma-aminobutyric acid A receptor, alpha 1
  • gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1
  • gamma-aminobutyric acid A receptor, alpha 1
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
  • GABAA alpha 1
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