FZD6 抗体
(Frizzled Family Receptor 6 (FZD6))
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011].
recommended
recommended
recommended
FZD6 适用: 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
FZD6 抗体 by 适用
Find FZD6 抗体 for a variety of species such as anti-Human FZD6, anti-Mouse FZD6, anti-Rat FZD6. The species listed below are among those available. Click on a link to go to the corresponding products.
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FZD6 抗体 by 克隆形成能力
Find available monoclonal or polyclonal FZD6 抗体. Click on a link to go to the corresponding products.
FZD6 抗体 by 克隆
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FZD6 抗体 by 标记
Find FZD6 抗体 with a specific conjugate such as Biotin, APC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular FZD6 抗体
Product
Reactivity
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Validations
Cat. No.
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Datasheet
Reactivity
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Application
IHC, ICC, IHC (p)
Validations
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
WB, ELISA, IHC, IF, ICC
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Cat. No.
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Quantity
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Datasheet
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WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p)
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
ABIN7238471
Quantity
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Datasheet
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Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Monkey, Pig, Rabbit, Rat
Application
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Validations
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Cat. No.
ABIN6743054
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IF
Validations
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Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC, IF
Validations
Cat. No.
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Quantity
50 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IF
Validations
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Quantity
50 μL
Datasheet
Datasheet
Reactivity
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Application
IP
Validations
Cat. No.
ABIN7452245
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
ELISA
Validations
Cat. No.
ABIN563592
Quantity
50 μL
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
Cat. No.
ABIN7468346
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
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Validations
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Quantity
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Datasheet
Datasheet
Latest Publications for our FZD6 抗体
: "Functional dissection of the N-terminal extracellular domains of Frizzled 6 reveals their roles for receptor localization and Dishevelled recruitment." in: The Journal of biological chemistry, Vol. 293, Issue 46, pp. 17875-17887, (2018) (PubMed).: "A role for core planar polarity proteins in cell contact-mediated orientation of planar cell division across the mammalian embryonic skin." in: Scientific reports, Vol. 7, Issue 1, pp. 1880, (2017) (PubMed).
: "Transcriptomic analysis comparing mouse strains with extreme total lung capacities identifies novel candidate genes for pulmonary function." in: Respiratory research, Vol. 18, Issue 1, pp. 152, (2017) (PubMed).
: "Cell and Tissue Scale Forces Coregulate Fgfr2-Dependent Tetrads and Rosettes in the Mouse Embryo." in: Biophysical journal, Vol. 112, Issue 10, pp. 2209-2218, (2017) (PubMed).
: "The spatio-temporal domains of Frizzled6 action in planar polarity control of hair follicle orientation." in: Developmental biology, Vol. 409, Issue 1, pp. 181-93, (2015) (PubMed).
: "Anisotropic stress orients remodelling of mammalian limb bud ectoderm." in: Nature cell biology, Vol. 17, Issue 5, pp. 569-79, (2015) (PubMed).
: "Otitis media in sperm-associated antigen 6 (Spag6)-deficient mice." in: PLoS ONE, Vol. 9, Issue 11, pp. e112879, (2014) (PubMed).
: "Restoration of WNT4 inhibits cell growth in leukemia-derived cell lines." in: BMC cancer, Vol. 13, pp. 557, (2013) (PubMed).
: "Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain." in: Development (Cambridge, England), Vol. 138, Issue 8, pp. 1607-17, (2011) (PubMed).
Aliases for FZD6 抗体
frizzled class receptor 6 (fzd6) 抗体frizzled class receptor 6 S homeolog (fzd6.S) 抗体
frizzled class receptor 6 (FZD6) 抗体
frizzled class receptor 6 (Fzd6) 抗体
frizzled-6 抗体
Frizzled-6 抗体
frizzled6 抗体
frz6 抗体
FZ-6 抗体
fz6 抗体
FZ6 抗体
Fz6 抗体
HFZ6 抗体
NDNC10 抗体
Xfrz6 抗体
zgc:65879 抗体
zgc:77440 抗体
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