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FYN 产品

(FYN Oncogene Related To SRC, FGR, YES (FYN))

Categories

This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008].

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Featured FYN Categories

FYN 抗体

High quality antibodies with extensive validation data.

FYN ELISA试剂盒

Reliable ELISA kits for a wide range of species.

FYN 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FYN 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), IP, ICC
Validations
  • (2)
  • (7)
Cat. No. ABIN94311
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (3)
  • (5)
Cat. No. ABIN969159
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (5)
Cat. No. ABIN6256757
Quantity 100 μL
Datasheet Datasheet

Recommended FYN ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (3)
Cat. No. ABIN4889771
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956014
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956013
Quantity 96 tests
Datasheet Datasheet

Recommended FYN 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
Cat. No. ABIN1354567
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123023
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354569
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our FYN Products

Nakanishi, Menju, Nishikawa, Takahashi, Miyata, Shikuma, Sowa, Imamura, Hamaji, Motoyama, Hijiya, Aoyama, Sato, Chen-Yoshikawa, Sonobe, Date: "The synergistic role of ATP-dependent drug efflux pump and focal adhesion signaling pathways in vinorelbine resistance in lung cancer." in: Cancer medicine, Vol. 7, Issue 2, pp. 408-419, (2018) (PubMed).

Grossman, Har-Paz, Gindi, Levi, Miller, Nevo, Galiani, Dekel, Shalgi: "Regulation of GVBD in mouse oocytes by miR-125a-3p and Fyn kinase through modulation of actin filaments." in: Scientific reports, Vol. 7, Issue 1, pp. 2238, (2017) (PubMed).

Miyamoto, Torii, Takada, Ohno, Saitoh, Nakamura, Ito, Ogata, Terada, Tanoue, Yamauchi: "Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination." in: Molecular biology of the cell, Vol. 26, Issue 19, pp. 3489-503, (2015) (PubMed).

Hu, Takano, Xiang, Gilkes, Luo, Semenza: "Hypoxia-inducible factors enhance glutamate signaling in cancer cells." in: Oncotarget, Vol. 5, Issue 19, pp. 8853-68, (2014) (PubMed).

Liu, Chen, Chau, Jan, Chen, Hsu, Lin, Juang, Lu, Cheng, Chen, Chang, Ting, Kao, Hsiao, Huang: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).

Taniguchi, Xia, Goldberg, Lee, Shah, Stavar, Masson, Momen, Shikatani, John, Husain, Fantus: "Inhibition of Src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice." in: Diabetes, Vol. 62, Issue 11, pp. 3874-86, (2013) (PubMed).

Jia, Pan, Ding, Rong, Liu, Geng, Qiao, Liang: "The N-terminal region of IFITM3 modulates its antiviral activity by regulating IFITM3 cellular localization." in: Journal of virology, Vol. 86, Issue 24, pp. 13697-707, (2012) (PubMed).

Queval, Nicolas, Beau: "Role of Src kinases in mobilization of glycosylphosphatidylinositol-anchored decay-accelerating factor by Dr fimbria-positive adhering bacteria." in: Infection and immunity, Vol. 79, Issue 7, pp. 2519-34, (2011) (PubMed).

Brignatz, Paronetto, Opi, Cappellari, Audebert, Feuillet, Bismuth, Roche, Arold, Sette, Collette: "Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn." in: Molecular and cellular biology, Vol. 29, Issue 24, pp. 6438-48, (2009) (PubMed).

Lu, Zhu, Cvrljevic, Huang, Sarkaria, Ahkavan, Dang, Dinca, Plaisier, Oderberg, Lee, Chen, Caldwell, Xie, Loo, Seligson, Chakravari, Lee, Weinmann, Cloughesy, Nelson, Bergers, Graeber, Furnari, James, Cavenee, Johns, Mischel: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." in: Cancer research, Vol. 69, Issue 17, pp. 6889-98, (2009) (PubMed).

Synonyms and alternative names related to FYN

FYN proto-oncogene, Src family tyrosine kinase (FYN), FYN proto-oncogene, Src family tyrosine kinase S homeolog (fyn.S), FYN proto-oncogene, Src family tyrosine kinase b (fynb), FYN proto-oncogene, Src family tyrosine kinase L homeolog (fyn.L), FYN proto-oncogene, Src family tyrosine kinase (Fyn), FYN proto-oncogene, Src family tyrosine kinase a (fyna), Fyn proto-oncogene (Fyn), AI448320, AW552119, c-fyn, cfyn-a, fyn, im:6908851, p59-FYN, PKC, si:dkey-119m7.5, SLK, SYN, zgc:86720, zgc:109996

Protein level used designations for FYN

  • protein-tyrosine kinase fyn
  • proto-oncogene tyrosine-protein kinase fyn
  • Fyn non-receptor tyrosine kinase
  • proto-oncogene c-Fynb
  • tyrosine-protein kinase fynb
  • FYN oncogene related to SRC, FGR, YES
  • proto-oncogene tyrosine-protein kinase fyn-like
  • tyrosine-protein kinase Fyn-like
  • p59-Fyn
  • proto-oncogene c-Fyn
  • proto-oncogene tyrosine-protein kinase Fyn
  • tyrosine-protein kinase Fyn
  • OKT3-induced calcium influx regulator
  • c-syn protooncogene
  • proto-oncogene Syn
  • src-like kinase
  • src/yes-related novel
  • tyrosine kinase p59fyn(T)
  • fyn proto-oncogene
  • c-fyn, fyn proto-oncogene
  • protein-tyrosine kinase
  • proto-oncogene c-Fyna
  • tyrosine-protein kinase fyna
  • Src Kinase p59
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