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FXR1 产品

(Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

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The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured FXR1 Categories

FXR1 抗体

High quality antibodies with extensive validation data.

FXR1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FXR1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (5)
Cat. No. ABIN7261882
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, FACS
Validations
  • (5)
Cat. No. ABIN185683
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7153147
Quantity 100 μg
Datasheet Datasheet

Recommended FXR1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6204426
Quantity 96 tests
Datasheet Datasheet

Recommended FXR1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354555
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1989821
Quantity 25 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421134
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FXR1 Products

Zhao, Xu, Yuan, Jiang, Zhou, Li, Yin, Zhou, Zhang, Wang: "8-Methoxypsoralen disrupts MDR3-mediated phospholipids efflux and bile acid homeostasis and its relevance to hepatotoxicity." in: Toxicology, Vol. 386, pp. 40-48, (2017) (PubMed).

Fischer-Kešo, Breuninger, Hofmann, Henn, Röhrig, Ströbel, Stoecklin, Hofmann: "Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins." in: Molecular and cellular biology, Vol. 34, Issue 23, pp. 4244-56, (2014) (PubMed).

Coffee, Tessier, Woodruff, Broadie: "Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P." in: Disease models & mechanisms, Vol. 3, Issue 7-8, pp. 471-85, (2010) (PubMed).

Darnell, Fraser, Mostovetsky, Darnell: "Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs." in: Human molecular genetics, Vol. 18, Issue 17, pp. 3164-77, (2009) (PubMed).

Purcell, Wray, Stone, Visscher, ODonovan, Sullivan, Sklar: "Common polygenic variation contributes to risk of schizophrenia and bipolar disorder." in: Nature, Vol. 460, Issue 7256, pp. 748-52, (2009) (PubMed).

Davidovic, Sacconi, Bechara, Delplace, Allegra, Desnuelle, Bardoni: "Alteration of expression of muscle specific isoforms of the fragile X related protein 1 (FXR1P) in facioscapulohumeral muscular dystrophy patients." in: Journal of medical genetics, Vol. 45, Issue 10, pp. 679-85, (2008) (PubMed).

Vasudevan, Steitz: "AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2." in: Cell, Vol. 128, Issue 6, pp. 1105-18, (2007) (PubMed).

Coon, Matsunami, Stevens, Miller, Pingree, Camp, Thomas, Krasny, Lainhart, Leppert, McMahon: "Evidence for linkage on chromosome 3q25-27 in a large autism extended pedigree." in: Human heredity, Vol. 60, Issue 4, pp. 220-6, (2006) (PubMed).

Synonyms and alternative names related to FXR1

FMR1 autosomal homolog 1 (FXR1), fragile X mental retardation, autosomal homolog 1 (fxr1), FMR1 autosomal homolog 1 (Fxr1), fragile X mental retardation, autosomal homolog 1 (FXR1), FMR1 autosomal homolog 1 (fxr1), fragile X mental retardation gene 1, autosomal homolog (Fxr1), FMR1 autosomal homolog 1 L homeolog (fxr1.L), FMR1 autosomal homolog 1 S homeolog (fxr1.S), 1110050J02Rik, 9530073J07Rik, AI851072, FXR1, fxr1, Fxr1h, fxr1h, FXR1P, Fxr1p, wu:fb16f11, wu:fd18c10, xfxr1, xFxr1p, XtFxr1p, zgc:66226

Protein level used designations for FXR1

  • fragile X mental retardation syndrome-related protein 1
  • hFXR1p
  • fragile X mental retardation gene 1, autosomal homolog
  • fragile X mental retardation-related protein 1
  • Fragile X mental retardation syndrome-related protein 1 homolog
  • fragile X mental retardation syndrome-related protein 1 homolog
  • fragile X mental retardation, autosomal homolog 1
  • fragile X mental retardation syndrome-related protein 1-like
  • fragile X mental retardation gene, autosomal homolog
  • fragile-X-related protein 1
  • mFxr1p
  • FXR1
  • fragile X mental retardation syndrome-related protein 1 homolog A
  • xFxr1p-A
  • fragile X-related protein
  • Fragile X mental retardation syndrome related protein 1
  • fragile X mental retardation syndrome-related protein 1 homolog B
  • xFxr1p-B
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