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FUS 蛋白

(Fused in Sarcoma (FUS))

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].

recommended

FUS Protein (AA 287-376) (His-IF2DI Tag) (ABIN7123020)

FUS 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB

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recommended

FUS Protein (Myc-DYKDDDDK Tag) (ABIN2721461)

FUS 宿主: 人宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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recommended

FUS Protein (AA 137-574) (His tag) (ABIN5714278)

FUS 宿主: Human respiratory syncytial virus B 宿主: 酵母菌 Recombinant > 90 % SDS

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FUS 蛋白 by Origin

Find FUS 蛋白 for a variety of species such as anti-Human FUS, anti-Canine Distemper Virus (CDV) FUS, anti-Human respiratory syncytial virus A FUS. The species listed below are among those available. Click on a link to go to the corresponding products.

FUS 蛋白 by Source

Here you will find FUS 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

FUS 蛋白 by 蛋白类型

Here you can find FUS 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

FUS 蛋白 by 应用范围

Find FUS 蛋白 validated for a specific application such as SDS, ELISA, AbP, STD. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular FUS 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

FUS Protein (AA 287-376) (His-IF2DI Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123020

Quantity 50 μg

Datasheet Datasheet

FUS Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2721461

Quantity 20 μg

Datasheet Datasheet

FUS Protein (AA 137-574) (His tag)

Reactivity Human respiratory syncytial virus B

Source Yeast

Validations

Cat. No. ABIN5714278

Quantity 100 μg

Datasheet Datasheet

FUS Protein (AA 27-529) (His tag)

Reactivity Human respiratory syncytial virus A

Source Yeast

Validations

Cat. No. ABIN5714158

Quantity 100 μg

Datasheet Datasheet

FUS Protein (AA 136-608) (His-SUMO Tag)

Reactivity Canine Distemper Virus (CDV)

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN5710740

Quantity 100 μg

Datasheet Datasheet

FUS Protein (AA 1-198, partial) (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1608021

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our FUS 蛋白

Bogaert, Boeynaems, Kato, Guo, Caulfield, Steyaert, Scheveneels, Wilmans, Haeck, Hersmus, Schymkowitz, Rousseau, Shorter, Callaerts, Robberecht, Van Damme, Van Den Bosch: "Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity." in: Cell reports, Vol. 24, Issue 3, pp. 529-537.e4, (2018) (PubMed).

Gorthi, Romero, Loranc, Cao, Lawrence, Goodale, Iniguez, Bernard, Masamsetti, Roston, Lawlor, Toretsky, Stegmaier, Lessnick, Chen, Bishop: "EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma." in: Nature, Vol. 555, Issue 7696, pp. 387-391, (2018) (PubMed).

Blokhuis, Koppers, Groen, van den Heuvel, Dini Modigliani, Anink, Fumoto, van Diggelen, Snelting, Sodaar, Verheijen, Demmers, Veldink, Aronica, Bozzoni, den Hertog, van den Berg, Pasterkamp: "Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways." in: Acta neuropathologica, Vol. 132, Issue 2, pp. 175-96, (2016) (PubMed).

Altmeyer, Neelsen, Teloni, Pozdnyakova, Pellegrino, Grøfte, Rask, Streicher, Jungmichel, Nielsen, Lukas: "Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)." in: Nature communications, Vol. 6, pp. 8088, (2015) (PubMed).

Groen, Fumoto, Blokhuis, Engelen-Lee, Zhou, van den Heuvel, Koppers, van Diggelen, van Heest, Demmers, Kirby, Shaw, Aronica, Spliet, Veldink, van den Berg, Pasterkamp: "ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN." in: Human molecular genetics, Vol. 22, Issue 18, pp. 3690-704, (2013) (PubMed).

Aliases for FUS 蛋白

FUS RNA binding protein (FUS) 蛋白
fused in sarcoma (Fus) 蛋白
FUS RNA binding protein (Fus) 蛋白
fused in sarcoma (FUS) 蛋白
ALS6 蛋白
D430004D17Rik 蛋白
D930039C12Rik 蛋白
ETM4 蛋白
FUS/TLS 蛋白
FUS1 蛋白
Fus1 蛋白
HNRNPP2 蛋白
POMP75 蛋白
TLS 蛋白
Tls 蛋白

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FUS 蛋白 by Origin

FUS 蛋白 by Source

FUS 蛋白 by 蛋白类型

FUS 蛋白 by 应用范围

Popular FUS 蛋白

Latest Publications for our FUS 蛋白

Aliases for FUS 蛋白

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