FUS 产品
(Fused in Sarcoma (FUS))
Categories
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].
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Featured FUS Categories
FUS 抗体
High quality antibodies with extensive validation data.
FUS ELISA试剂盒
Reliable ELISA kits for a wide range of species.
FUS 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FUS 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Dog, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN2778717
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, FACS
Validations
- (7)
Cat. No.
ABIN3031006
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (4)
Cat. No.
ABIN6140818
Quantity
100 μL
Datasheet
Datasheet
Recommended FUS ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966914
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1156242
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1156240
Quantity
96 tests
Datasheet
Datasheet
Recommended FUS 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123020
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
- (1)
Cat. No.
ABIN2721461
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human respiratory syncytial virus B
Source
Yeast
Validations
- (1)
Cat. No.
ABIN5714278
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our FUS Products
: "FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I-induced DNA breakage and transcriptional stress." in: Life science alliance, Vol. 2, Issue 2, (2019) (PubMed).: "PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA." in: Cell reports, Vol. 27, Issue 6, pp. 1809-1821.e5, (2019) (PubMed).
: "Expanded polyglutamine impairs normal nuclear distribution of fused in sarcoma and poly (rC)-binding protein 1 in Huntington's disease." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 39, Issue 5, pp. 358-367, (2019) (PubMed).
: "Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS." in: Acta neuropathologica communications, Vol. 7, Issue 1, pp. 18, (2019) (PubMed).
: "Cytoplasmic Restriction of Mutated SOD1 Impairs the DNA Repair Process in Spinal Cord Neurons." in: Cells, Vol. 8, Issue 12, (2019) (PubMed).
: "Lymphoblastoid cell lines as a model to understand amyotrophic lateral sclerosis disease mechanisms." in: Disease models & mechanisms, Vol. 11, Issue 3, (2018) (PubMed).
: "ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity." in: eLife, Vol. 7, (2018) (PubMed).
: "Human proteins that interact with RNA/DNA hybrids." in: Genome research, Vol. 28, Issue 9, pp. 1405-1414, (2018) (PubMed).
: "Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity." in: Cell reports, Vol. 24, Issue 3, pp. 529-537.e4, (2018) (PubMed).
: "EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma." in: Nature, Vol. 555, Issue 7696, pp. 387-391, (2018) (PubMed).
Synonyms and alternative names related to FUS
FUS RNA binding protein (FUS), fused in sarcoma (Fus), FUS RNA binding protein (Fus), fused in sarcoma (FUS), ALS6, D430004D17Rik, D930039C12Rik, ETM4, FUS/TLS, FUS1, Fus1, HNRNPP2, POMP75, TLS, TlsProtein level used designations for FUS
- 75 kDa DNA-pairing protein
- RNA-binding protein FUS
- fus-like protein
- fusion gene in myxoid liposarcoma
- heterogeneous nuclear ribonucleoprotein P2
- oncogene FUS
- oncogene TLS
- translocated in liposarcoma protein
- fusion, derived from t(12;16) malignant liposarcoma
- hnRNP P2
- pigpen protein
- protein pigpen
- translocated in liposarcoma
- fusion
- pigpen
- fusion (involved in t(12;16) in malignant liposarcoma)
- 16) in malignant liposarcoma)
- 16) malignant liposarcoma
- fusion (involved in t(12
- fusion, derived from t(12
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