FTH1 产品
(Ferritin, Heavy Polypeptide 1 (FTH1))
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This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
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Featured FTH1 Categories
FTH1 抗体
High quality antibodies with extensive validation data.
FTH1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
FTH1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FTH1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7435313
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (9)
Cat. No.
ABIN7437164
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Pig
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7440041
Quantity
100 μL
Datasheet
Datasheet
Recommended FTH1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
Cat. No.
ABIN6955747
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955749
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966709
Quantity
96 tests
Datasheet
Datasheet
Recommended FTH1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354475
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Source
Escherichia coli (E. coli)
Validations
- (3)
- (1)
Cat. No.
ABIN1095588
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505081
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our FTH1 Products
: "Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy." in: The EMBO journal, Vol. 40, Issue 14, pp. e105985, (2021) (PubMed).: "Salinomycin kills cancer stem cells by sequestering iron in lysosomes." in: Nature chemistry, Vol. 9, Issue 10, pp. 1025-1033, (2019) (PubMed).
: "Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9." in: Cell reports, Vol. 20, Issue 10, pp. 2341-2356, (2018) (PubMed).
: "Impact of TET2 deficiency on iron metabolism in erythroblasts." in: Experimental hematology, Vol. 49, pp. 56-67.e5, (2017) (PubMed).
: "Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy." in: The EMBO journal, Vol. 36, Issue 1, pp. 42-60, (2017) (PubMed).
: "MR molecular imaging of tumours using ferritin heavy chain reporter gene expression mediated by the hTERT promoter." in: European radiology, Vol. 26, Issue 11, pp. 4089-4097, (2016) (PubMed).
: "Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis." in: Toxicology and applied pharmacology, Vol. 301, pp. 50-60, (2016) (PubMed).
: "Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis." in: eLife, Vol. 4, (2016) (PubMed).
: "The Oral Iron Chelator, Deferasirox, Reverses the Age-Dependent Alterations in Iron and Amyloid-β Homeostasis in Rat Brain: Implications in the Therapy of Alzheimer's Disease." in: Journal of Alzheimer's disease : JAD, Vol. 49, Issue 3, pp. 681-93, (2015) (PubMed).
: "Methemoglobin-induced signaling and chemokine responses in human alveolar epithelial cells." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 1, pp. L88-100, (2014) (PubMed).
Synonyms and alternative names related to FTH1
ferritin heavy chain 1 (FTH1), ferritin, heavy polypeptide 1 L homeolog (fth1.L), ferritin, heavy polypeptide 1 S homeolog (fth1.S), ferritin heavy polypeptide 1 (Fth1), ferritin heavy chain 1 (Fth1), ferritin, heavy polypeptide 1a (fth1a), ferritin (EAMY_RS19690), ferritin, heavy polypeptide 1 (fth1), tudor domain containing 9 (TDRD9), ferritin, heavy polypeptide 1 (FTH1), ferritin, heavy polypeptide 1 a (fth1a), apoferritin, fb06g09, ferritin, FHC, fhc, FTH, fth, Fth, fth1, fth1b, FTHL6, fthl6, ftn-2, HFt, hm:zeh1145, MFH, PIG15, pig15, PLIF, plif, wu:fb06g09, wu:fq18c10, zeh1145Protein level used designations for FTH1
- apoferritin
- cell proliferation-inducing gene 15 protein
- ferritin H subunit
- ferritin heavy chain
- placenta immunoregulatory factor
- proliferation-inducing protein 15
- ferritin H chain
- XL2-17
- ferritin H subunit A
- ferritin heavy chain 2
- ferritin heavy chain A
- ferritin H subunit B
- ferritin heavy chain 1
- ferritin heavy chain B
- ferritin, heavy polypeptide 1 b
- ferritin heavy polypeptide 1
- ferritin heavy-chain
- H-ferritin
- Ferritin subunit H
- ferritin, heavy polypeptide 1
- tudor domain containing 9
- Ferritin H subunit
- ferritin heavy chain 1 a
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