FOXN1 产品
(Forkhead Box N1 (FOXN1))
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The protein encoded by this gene is part of the forkhead family or 'winged-helix' transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. This gene family has over 100 members, subdivided into classes (A-Q) based on phylogeny. The encoded protein is proposed to regulate development of the thymus and differentiation of keratinocytes. Mutations in this gene cause severe primary T-cell immunodeficiency and congenital alopecia. In mouse mutations of this gene underlie the phenotype of the nude mouse, which has been widely used as a model system in oncology, immunology, dermatology, and transplantation studies. In humans mutations in this gene have been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013].
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Featured FOXN1 Categories
Recommended FOXN1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (3)
Cat. No.
ABIN1387592
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7153070
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN185069
Quantity
100 μg
Datasheet
Datasheet
Recommended FOXN1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1787167
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092648
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3135432
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our FOXN1 Products
: "EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. ..." in: The Journal of experimental medicine, Vol. 214, Issue 3, pp. 623-637, (2017) (PubMed).: "Forkhead/winged-helix transcription factor Whn regulates hair keratin gene expression: molecular analysis of the nude skin phenotype." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 217, Issue 4, pp. 368-76, (2000) (PubMed).
Synonyms and alternative names related to FOXN1
forkhead box N1 (FOXN1), forkhead box N1 (foxn1), forkhead box N1 (foxN1), forkhead box protein N1 (LOC100125524), forkhead box N1 (Foxn1), D11Bhm185e, Fkh19, FKHL20, foxN, FOXN1, foxN1, foxn1, HFH-11, Hfh11, nu, nude, Rnu, RONU, WHN, Whn, whnbProtein level used designations for FOXN1
- forkhead box protein N1
- forkhead box N1
- forkhead box N protein
- forkhead box protein N1-like
- transcription factor Forkhead box protein N1
- Rowett nude
- winged helix nude
- winged-helix nude
- winged-helix transcription factor nude
- HNF-3/forkhead homolog 11
- hepatocyte nuclear factor 3 forkhead homolog 11
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