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FLVCR 产品

(Feline Leukemia Virus Subgroup C Cellular Receptor 1 (FLVCR1))

Categories

This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein is a heme transporter that may play a critical role in erythropoiesis by protecting developing erythroid cells from heme toxicity. This gene may play a role in posterior column ataxia with retinitis pigmentosa and the hematological disorder Diamond-Blackfan syndrome. [provided by RefSeq, Jan 2011].

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Featured FLVCR Categories

FLVCR 抗体

High quality antibodies with extensive validation data.

FLVCR 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FLVCR 抗体

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Cat. No. ABIN565398
Quantity 100 μg
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Cat. No. ABIN526038
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Cat. No. ABIN526037
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Recommended FLVCR 蛋白

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Cat. No. ABIN1354230
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Latest Publications for our FLVCR Products

Chiabrando, Marro, Mercurio, Giorgi, Petrillo, Vinchi, Fiorito, Fagoonee, Camporeale, Turco, Merlo, Silengo, Altruda, Pinton, Tolosano: "The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation." in: The Journal of clinical investigation, Vol. 122, Issue 12, pp. 4569-79, (2012) (PubMed).

Alves, Costa, Sorgine, Nascimento-Silva, Teodosio, Bárcena, Castro-Faria-Neto, Bozza, Orfao, Oliveira, Maya-Monteiro: "Heme-oxygenases during erythropoiesis in K562 and human bone marrow cells." in: PLoS ONE, Vol. 6, Issue 7, pp. e21358, (2011) (PubMed).

Rey, Duffy, Brown, Kennedy, Dick, Dror, Tailor: "Enhanced alternative splicing of the FLVCR1 gene in Diamond Blackfan anemia disrupts FLVCR1 expression and function that are critical for erythropoiesis." in: Haematologica, Vol. 93, Issue 11, pp. 1617-26, (2008) (PubMed).

Quigley, Yang, Worthington, Phillips, Sabo, Sabath, Berg, Sassa, Wood, Abkowitz: "Identification of a human heme exporter that is essential for erythropoiesis." in: Cell, Vol. 118, Issue 6, pp. 757-66, (2004) (PubMed).

Synonyms and alternative names related to FLVCR

feline leukemia virus subgroup C cellular receptor 1 (FLVCR1), feline leukemia virus subgroup C cellular receptor 1 (flvcr1), feline leukemia virus subgroup C cellular receptor 1 (Flvcr1), 9630055N22Rik, AXPC1, FLVCR, Flvcr1, MFSD7B, PCA, PCARP, si:ch211-147d7.6

Protein level used designations for FLVCR

  • feline leukemia virus subgroup C cellular receptor 1
  • feline leukemia virus subgroup C receptor-related protein 1
  • feline leukemia virus subgroup C receptor-related protein 1-like
  • feline leukemia virus subgroup C cellular receptor
  • eline leukemia virus subgroup C cellular receptor 1
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