FIP1L1 抗体
(FIP1 Like 1 (FIP1L1))
This gene encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylates the 3' end of mRNA precursors. This gene, the homolog of yeast Fip1 (factor interacting with PAP), binds to U-rich sequences of pre-mRNA and stimulates poly(A) polymerase activity. Its N-terminus contains a PAP-binding site and its C-terminus an RNA-binding domain. An interstitial chromosomal deletion on 4q12 creates an in-frame fusion of human genes FIP1L1 and PDGFRA (platelet-derived growth factor receptor, alpha). The FIP1L1-PDGFRA fusion gene encodes a constitutively activated tyrosine kinase that joins the first 233 amino acids of FIP1L1 to the last 523 amino acids of PDGFRA. This gene fusion and chromosomal deletion is the cause of some forms of idiopathic hypereosinophilic syndrome (HES). This syndrome, recently reclassified as chronic eosinophilic leukemia (CEL), is responsive to treatment with tyrosine kinase inhibitors. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].
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FIP1L1 抗体 by 适用
Find FIP1L1 抗体 for a variety of species such as anti-Human FIP1L1, anti-Mouse FIP1L1, anti-Rat FIP1L1. The species listed below are among those available. Click on a link to go to the corresponding products.
FIP1L1 抗体 by 应用范围
Find FIP1L1 抗体 validated for a specific application such as WB, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.
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FIP1L1 抗体 by 抗原表位
Find FIP1L1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
FIP1L1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal FIP1L1 抗体. Click on a link to go to the corresponding products.
FIP1L1 抗体 by 克隆
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Popular FIP1L1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
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Quantity
200 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN6140640
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA
Validations
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Cat. No.
ABIN529371
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IF, IC
Validations
- (3)
Cat. No.
ABIN7306954
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6736286
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN633439
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC
Validations
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Cat. No.
ABIN2776582
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (p), IF (cc), ELISA, IHC (p), IHC (fro), ICC
Validations
Cat. No.
ABIN1714160
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1700658
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN1698845
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN5002712
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN5002713
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN1695208
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN2813275
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN1693391
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our FIP1L1 抗体
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).Aliases for FIP1L1 抗体
factor interacting with PAPOLA and CPSF1 (fip1l1) 抗体factor interacting with PAPOLA and CPSF1 (FIP1L1) 抗体
factor interacting with PAPOLA and CPSF1 S homeolog (fip1l1.S) 抗体
factor interacting with PAPOLA and CPSF1 (Fip1l1) 抗体
FIP1 like 1 (S. cerevisiae) (Fip1l1) 抗体
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fip1l1 抗体
hFip1 抗体
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zgc:103421 抗体
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