Filamin A 抗体
(Filamin A, alpha (FLNA))
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].
recommended
recommended
recommended
FLNA 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 4E10-1B2 unconjugated
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Reactivity
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Datasheet
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
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Quantity
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WB, ELISA, IHC (p), PLA
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Cat. No.
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Quantity
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WB, IHC, ELISA, IF, ICC
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
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Cat. No.
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Cat. No.
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Cat. No.
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Datasheet
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Cat. No.
ABIN6140677
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IF/ICC, FACS
Validations
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Cat. No.
ABIN3003482
Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IHC (p), EIA
Validations
- (3)
Cat. No.
ABIN782404
Quantity
50 μg
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Quantity
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Datasheet
Datasheet
Latest Publications for our Filamin A 抗体
: "DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk." in: eLife, Vol. 5, (2016) (PubMed).: "Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors." in: Journal of molecular endocrinology, Vol. 58, Issue 2, pp. 91-103, (2016) (PubMed).
: "Familial periventricular nodular heterotopia, epilepsy and Melnick-Needles Syndrome caused by a single FLNA mutation with combined gain-of-function and loss-of-function effects." in: Journal of medical genetics, Vol. 52, Issue 6, pp. 405-12, (2015) (PubMed).
: "Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119686, (2015) (PubMed).
: "Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-?B Activation in Melanoma Cells by Inhibition of Akt Signaling." in: Molecular and cellular biology, (2015) (PubMed).
: "Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells." in: Endocrinology, Vol. 155, Issue 8, pp. 2932-41, (2014) (PubMed).
: "Novel no-stop FLNA mutation causes multi-organ involvement in males." in: American journal of medical genetics. Part A, Vol. 161A, Issue 9, pp. 2376-84, (2013) (PubMed).
: "Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 18, Issue 9, pp. 810-22, (2013) (PubMed).
: "Filamin-A is essential for dopamine d2 receptor expression and signaling in tumorous lactotrophs." in: The Journal of clinical endocrinology and metabolism, Vol. 97, Issue 3, pp. 967-77, (2012) (PubMed).
: "A chemical cross-linking method for the analysis of binding partners of heat shock protein-90 in intact cells." in: BioTechniques, pp. 1-7, (2012) (PubMed).
Aliases for Filamin A 抗体
filamin A (FLNA) 抗体filamin A, alpha (actin binding protein 280) (flna) 抗体
filamin, alpha (Flna) 抗体
filamin A (Flna) 抗体
filamin-A (LOC587317) 抗体
filamin A (flna) 抗体
cheerio (cher) 抗体
filamin-A (LOC100380643) 抗体
ABP-280 抗体
ABPX 抗体
CG3937 抗体
Cher 抗体
CSBS 抗体
CVD1 抗体
Dilp2 抗体
Dmel\\CG3937 抗体
F730004A14Rik 抗体
fb98b06 抗体
Fil 抗体
filamin-1 抗体
FLN 抗体
FLN-A 抗体
FLN1 抗体
Fln1 抗体
FMD 抗体
joy 抗体
MGC147094 抗体
MNS 抗体
NHBP 抗体
OPD 抗体
OPD1 抗体
OPD2 抗体
RGD1560614 抗体
sko 抗体
wu:fb98b06 抗体
wu:fd09g03 抗体
wu:fd49a06 抗体
XLVD 抗体
XMVD 抗体
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