Filamin A 产品
(Filamin A, alpha (FLNA))
Categories
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].
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Featured Filamin A Categories
Filamin A 抗体
High quality antibodies with extensive validation data.
Filamin A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Filamin A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Filamin A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7440788
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (6)
Cat. No.
ABIN7259092
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), PLA
Validations
- (8)
- (5)
Cat. No.
ABIN560922
Quantity
100 μg
Datasheet
Datasheet
Recommended Filamin A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955914
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN512498
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Guinea Pig
Analytical Method
Quantitative
Validations
Cat. No.
ABIN776806
Quantity
96 tests
Datasheet
Datasheet
Recommended Filamin A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354202
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2721188
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7412995
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Filamin A Products
: "DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk." in: eLife, Vol. 5, (2016) (PubMed).: "Filamin A (FLNA) modulates chemosensitivity to docetaxel in triple-negative breast cancer through the MAPK/ERK pathway." in: Tumour biology, Vol. 37, Issue 4, pp. 5107-15, (2016) (PubMed).
: "Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors." in: Journal of molecular endocrinology, Vol. 58, Issue 2, pp. 91-103, (2016) (PubMed).
: "Familial periventricular nodular heterotopia, epilepsy and Melnick-Needles Syndrome caused by a single FLNA mutation with combined gain-of-function and loss-of-function effects." in: Journal of medical genetics, Vol. 52, Issue 6, pp. 405-12, (2015) (PubMed).
: "Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119686, (2015) (PubMed).
: "Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-?B Activation in Melanoma Cells by Inhibition of Akt Signaling." in: Molecular and cellular biology, (2015) (PubMed).
: "S6K is a morphogenic protein with a mechanism involving Filamin-A phosphorylation and phosphatidic acid binding." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 4, pp. 1299-313, (2015) (PubMed).
: "Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells." in: Endocrinology, Vol. 155, Issue 8, pp. 2932-41, (2014) (PubMed).
: "Novel no-stop FLNA mutation causes multi-organ involvement in males." in: American journal of medical genetics. Part A, Vol. 161A, Issue 9, pp. 2376-84, (2013) (PubMed).
: "Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 18, Issue 9, pp. 810-22, (2013) (PubMed).
Synonyms and alternative names related to Filamin A
filamin A (FLNA), filamin A, alpha (actin binding protein 280) (flna), filamin, alpha (Flna), filamin A (Flna), filamin-A (LOC587317), filamin A (flna), cheerio (cher), filamin-A (LOC100380643), ABP-280, ABPX, CG3937, Cher, CSBS, CVD1, Dilp2, Dmel\\CG3937, F730004A14Rik, fb98b06, Fil, filamin-1, FLN, FLN-A, FLN1, Fln1, FMD, joy, MGC147094, MNS, NHBP, OPD, OPD1, OPD2, RGD1560614, sko, wu:fb98b06, wu:fd09g03, wu:fd49a06, XLVD, XMVDProtein level used designations for Filamin A
- actin binding protein 280
- alpha-filamin
- endothelial actin-binding protein
- filamin-1
- filamin-A
- non-muscle filamin
- filamin A, alpha (actin binding protein 280)
- fd09g03
- FLN-A
- GENA 379
- actin-binding protein 280
- dilated pupils 2
- filamin A
- Endothelial actin-binding protein 280)
- filamin, alpha
- filamin A, alpha
- CG3937-PA
- CG3937-PB
- CG3937-PF
- CG3937-PG
- CG3937-PH
- CG3937-PI
- CG3937-PK
- CG3937-PL
- CG3937-PM
- CG3937-PN
- Filamin-1
- Filamin-A
- cher-PA
- cher-PB
- cher-PF
- cher-PG
- cher-PH
- cher-PI
- cher-PK
- cher-PL
- cher-PM
- cher-PN
- filamin
- filamin B
- filamin isoform B
- filamin-240
- shi kong
- 450 kDa protein
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