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FIG4 抗体

(FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq, Jul 2008].
FIG4 抗体  (Center) FIG4 抗体  (Center) FIG4 抗体 (Center) (ABIN2856730)

FIG4 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated

FIG4 抗体  (AA 341-390) FIG4 抗体  (AA 341-390) FIG4 抗体 (AA 341-390) (ABIN7181220)

FIG4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

FIG4 抗体  (AA 608-907) FIG4 抗体  (AA 608-907) FIG4 抗体 (AA 608-907) (ABIN7267203)

FIG4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

FIG4 抗体 by 适用

Find FIG4 抗体 for a variety of species such as anti-Human FIG4, anti-Mouse FIG4, anti-Rat FIG4. The species listed below are among those available. Click on a link to go to the corresponding products.

FIG4 抗体 by 应用范围

Find FIG4 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

FIG4 抗体 by 抗体来源

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FIG4 抗体 by 抗原表位

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FIG4 抗体 by 克隆形成能力

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FIG4 抗体 by 克隆

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FIG4 抗体 by 标记

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Popular FIG4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), ICC, IF
Validations
  • (3)
Cat. No. ABIN2856730
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7181220
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7267203
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
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  • (2)
Cat. No. ABIN1537627
Quantity 400 μL
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
Cat. No. ABIN1385590
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1392763
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1392762
Quantity 100 μL
Datasheet Datasheet
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Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN5002696
Quantity 100 μL
Datasheet Datasheet
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Application WB, IF (cc), IF (p)
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Cat. No. ABIN5002697
Quantity 100 μL
Datasheet Datasheet
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Application WB, IF (cc), IF (p)
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Cat. No. ABIN1392759
Quantity 100 μL
Datasheet Datasheet
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Application WB, IF (cc), IF (p)
Validations
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Quantity 100 μL
Datasheet Datasheet
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Application WB, IF (cc), IF (p)
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Cat. No. ABIN2813263
Quantity 100 μL
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Quantity 100 μL
Datasheet Datasheet
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Application WB, IF (cc), IF (p)
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Quantity 100 μL
Datasheet Datasheet
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Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1410651
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our FIG4 抗体

Vaccari, Carbone, Previtali, Mironova, Alberizzi, Noseda, Rivellini, Bianchi, Del Carro, DAntonio, Lenk, Wrabetz, Giger, Meisler, Bolino: "Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy." in: Human molecular genetics, Vol. 24, Issue 2, pp. 383-96, (2014) (PubMed).

de Kovel, Meisler, Brilstra, van Berkestijn, van t Slot, van Lieshout, Nijman, OBrien, Hammer, Estacion, Waxman, Dib-Hajj, Koeleman: "Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy." in: Epilepsy research, Vol. 108, Issue 9, pp. 1511-8, (2014) (PubMed).

Reifler, Lenk, Li, Groom, Brooks, Wilson, Bowerson, Dirksen, Meisler, Dowling: "Murine Fig4 is dispensable for muscle development but required for muscle function." in: Skeletal muscle, Vol. 3, Issue 1, pp. 21, (2013) (PubMed).

Tahtouh, Elkins, Filippakopoulos, Soundararajan, Burgy, Durieu, Cochet, Schmid, Lo, Delhommel, Oberholzer, Pearl, Carreaux, Bazureau, Knapp, Meijer: "Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B." in: Journal of medicinal chemistry, Vol. 55, Issue 21, pp. 9312-30, (2012) (PubMed).

Zolov, Bridges, Zhang, Lee, Riehle, Verma, Lenk, Converso-Baran, Weide, Albin, Saltiel, Meisler, Russell, Weisman: "In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 43, pp. 17472-7, (2012) (PubMed).

Lenk, Ferguson, Chow, Jin, Jones, Grant, Zolov, Winters, Giger, Dowling, Weisman, Meisler: "Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J." in: PLoS genetics, Vol. 7, Issue 6, pp. e1002104, (2011) (PubMed).

Yan, Guo, Zhang, Bai, Wang, Li: "Trauma does not accelerate neuronal degeneration in Fig4 insufficient mice." in: Journal of the neurological sciences, Vol. 312, Issue 1-2, pp. 102-7, (2011) (PubMed).

Vaccari, Dina, Tronchère, Kaufman, Chicanne, Cerri, Wrabetz, Payrastre, Quattrini, Weisman, Meisler, Bolino: "Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies." in: PLoS genetics, Vol. 7, Issue 10, pp. e1002319, (2011) (PubMed).

Aliases for FIG4 抗体

FIG4 phosphoinositide 5-phosphatase (Fig4) 抗体
FIG4 phosphoinositide 5-phosphatase (FIG4) 抗体
A530089I17Rik 抗体
AI326867 抗体
ALS11 抗体
CMT4J 抗体
dJ249I4.1 抗体
KIAA0274 抗体
Kiaa0274 抗体
RGD1311375 抗体
Sac3 抗体
SAC3 抗体
YVS 抗体
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