FGFR3 抗体
(Fibroblast Growth Factor Receptor 3 (FGFR3))
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Jul 2009].
recommended
FGFR3 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2H10B4 unconjugated
recommended
recommended
FGFR3 抗体 by 适用
Find FGFR3 抗体 for a variety of species such as anti-Human FGFR3, anti-Mouse FGFR3, anti-Rat FGFR3. The species listed below are among those available. Click on a link to go to the corresponding products.
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Find FGFR3 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
FGFR3 抗体 by 克隆形成能力
Find available monoclonal or polyclonal FGFR3 抗体. Click on a link to go to the corresponding products.
FGFR3 抗体 by 克隆
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FGFR3 抗体 by Fragment
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Latest Publications for our FGFR3 抗体
: "A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells." in: Stem cell research & therapy, Vol. 10, Issue 1, pp. 99, (2019) (PubMed).: "The Neonatal and Adult Human Testis Defined at the Single-Cell Level." in: Cell reports, Vol. 26, Issue 6, pp. 1501-1517.e4, (2019) (PubMed).
: "FGF23 is synthesised locally by renal tubules and activates injury-primed fibroblasts." in: Scientific reports, Vol. 7, Issue 1, pp. 3345, (2018) (PubMed).
: "Biglycan is a novel binding partner of fibroblast growth factor receptor 3c (FGFR3c) in the human testis." in: Molecular and cellular endocrinology, Vol. 399, pp. 235-43, (2014) (PubMed).
: "Selenium induces a multi-targeted cell death process in addition to ROS formation." in: Journal of cellular and molecular medicine, Vol. 18, Issue 4, pp. 671-84, (2014) (PubMed).
: "Identification of autocrine growth factors secreted by CHO cells for applications in single-cell cloning media." in: Journal of proteome research, Vol. 12, Issue 7, pp. 3496-510, (2013) (PubMed).
: "Fibroblast growth factor-2 (Fgf2) is an important factor that maintains cellular immaturity and contributes to aggressiveness of osteosarcoma." in: Molecular cancer research : MCR, (2012) (PubMed).
: "Mild isolated craniosynostosis due to a novel FGFR3 mutation, p.Ala334Thr." in: American journal of medical genetics. Part A, Vol. 155A, Issue 12, pp. 3050-3, (2011) (PubMed).
: "The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival." in: Leukemia, Vol. 25, Issue 3, pp. 538-50, (2011) (PubMed).
: "Clinical and molecular diagnosis of the skeletal dysplasias associated with mutations in the gene encoding Fibroblast Growth Factor Receptor 3 (FGFR3) in Portugal." in: Clinical genetics, Vol. 75, Issue 2, pp. 150-6, (2009) (PubMed).
Aliases for FGFR3 抗体
fibroblast growth factor receptor 3 (FGFR3) 抗体fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog (fgfr3.S) 抗体
fibroblast growth factor receptor 3 (Fgfr3) 抗体
fibroblast growth factor receptor 3 (fgfr3) 抗体
ACH 抗体
CD333 抗体
CEK2 抗体
fc27h01 抗体
Fgfr-3 抗体
FGFR3 抗体
Flg-2 抗体
FR3 抗体
HBGFR 抗体
HSFGFR3EX 抗体
JTK4 抗体
LOC100034114 抗体
Mfr3 抗体
sam3 抗体
wu:fc27h01 抗体
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