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FEZ1 产品

(Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))

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This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008].

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Featured FEZ1 Categories

FEZ1 抗体

High quality antibodies with extensive validation data.

FEZ1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

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Latest Publications for our FEZ1 Products

McKnight, Jefferies, Alemu, Saunders, Howell, Johansen, Tooze: "Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC." in: The EMBO journal, Vol. 31, Issue 8, pp. 1931-46, (2012) (PubMed).

Kang, Burdick, Kim, Duan, Guo, Sailor, Jung, Ganesan, Choi, Pradhan, Lu, Avramopoulos, Christian, Malhotra, Song, Ming: "Interaction between FEZ1 and DISC1 in regulation of neuronal development and risk for schizophrenia." in: Neuron, Vol. 72, Issue 4, pp. 559-71, (2011) (PubMed).

Hiraoka, Okumura, Kishimoto: "Turn motif phosphorylation negatively regulates activation loop phosphorylation in Akt." in: Oncogene, Vol. 30, Issue 44, pp. 4487-97, (2011) (PubMed).

Blasius, Cai, Jih, Toret, Verhey: "Two binding partners cooperate to activate the molecular motor Kinesin-1." in: The Journal of cell biology, Vol. 176, Issue 1, pp. 11-7, (2007) (PubMed).

Suzuki, Okada, Semba, Orba, Yamanouchi, Endo, Tanaka, Fujita, Kuroda, Nagashima, Sawa: "Identification of FEZ1 as a protein that interacts with JC virus agnoprotein and microtubules: role of agnoprotein-induced dissociation of FEZ1 from microtubules in viral propagation." in: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24948-56, (2005) (PubMed).

Miyoshi, Honda, Baba, Taniguchi, Oono, Fujita, Kuroda, Katayama, Tohyama: "Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth." in: Molecular psychiatry, Vol. 8, Issue 7, pp. 685-94, (2003) (PubMed).

Ishii, Baffa, Numata, Murakumo, Rattan, Inoue, Mori, Fidanza, Alder, Croce: "The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 7, pp. 3928-33, (1999) (PubMed).

Kuroda, Nakagawa, Tokunaga, Tatematsu, Tanizawa: "Mammalian homologue of the Caenorhabditis elegans UNC-76 protein involved in axonal outgrowth is a protein kinase C zeta-interacting protein." in: The Journal of cell biology, Vol. 144, Issue 3, pp. 403-11, (1999) (PubMed).

Bloom, Horvitz: "The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 7, pp. 3414-9, (1997) (PubMed).

MacGrogan, Levy, Bova, Isaacs, Bookstein: "Structure and methylation-associated silencing of a gene within a homozygously deleted region of human chromosome band 8p22." in: Genomics, Vol. 35, Issue 1, pp. 55-65, (1996) (PubMed).

Synonyms and alternative names related to FEZ1

fasciculation and elongation protein zeta 1 (FEZ1), fasciculation and elongation protein zeta 1 (zygin I) (Fez1), fasciculation and elongation protein zeta 1 (Fez1), fasciculation and elongation protein zeta 1 (zygin I) (fez1), fasciculation and elongation protein zeta 1 L homeolog (fez1.L), fez1, UNC-76, UNC76, wu:fj14c12, xfez1, zgc:73258

Protein level used designations for FEZ1

  • fasciculation and elongation protein zeta-1
  • zygin I
  • zygin-1
  • protein kinase C-binding protein Zeta1
  • zygin 1
  • fasciculation and elongation protein zeta 1 (zygin I)
  • fasciculation and elongation protein zeta 1 L homeolog
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