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FES 产品

(Feline Sarcoma Oncogene (FES))
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009].

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Featured FES Categories

FES 抗体

High quality antibodies with extensive validation data.

FES ELISA试剂盒

Reliable ELISA kits for a wide range of species.

FES 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FES 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7174019
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN560862
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
  • (2)
Cat. No. ABIN969134
Quantity 100 μL
Datasheet Datasheet

Recommended FES ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648335
Quantity 96 tests
Datasheet Datasheet

Recommended FES 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
Cat. No. ABIN1353967
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5508929
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7416373
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FES Products

Ye, Kantonen, Henkels, Gomez-Cambronero: "A new signaling pathway (JAK-Fes-phospholipase D) that is enhanced in highly proliferative breast cancer cells." in: The Journal of biological chemistry, Vol. 288, Issue 14, pp. 9881-91, (2013) (PubMed).

Álvarez-Errico, Oliver-Vila, Ainsua-Enrich, Gilfillan, Picado, Sayós, Martín: "CD84 negatively regulates IgE high-affinity receptor signaling in human mast cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 5577-86, (2011) (PubMed).

Loriaux, Levine, Tyner, Fröhling, Scholl, Stoffregen, Wernig, Erickson, Eide, Berger, Bernard, Griffin, Stone, Lee, Meyerson, Heinrich, Deininger, Gilliland, Druker: "High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia." in: Blood, Vol. 111, Issue 9, pp. 4788-96, (2008) (PubMed).

Xiang, Zhao, Mitaksov, Fremont, Kasai, Molitoris, Ries, Miner, McLellan, DiPersio, Link, Payton, Graubert, Watson, Shannon, Heath, Nagarajan, Mardis, Wilson, Ley, Tomasson: "Identification of somatic JAK1 mutations in patients with acute myeloid leukemia." in: Blood, Vol. 111, Issue 9, pp. 4809-12, (2008) (PubMed).

Delfino, Stevenson, Smithgall: "A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer." in: The Journal of biological chemistry, Vol. 281, Issue 13, pp. 8829-35, (2006) (PubMed).

Durfee, Rivard: "Design and simulation of a pneumatic, stored-energy, hybrid orthosis for gait restoration." in: Journal of biomechanical engineering, Vol. 127, Issue 6, pp. 1014-9, (2006) (PubMed).

Vitenzon, Mironov, Petrushanskaya: "Functional electrostimulation of muscles as a method for restoring motor functions." in: Neuroscience and behavioral physiology, Vol. 35, Issue 7, pp. 709-14, (2006) (PubMed).

Rossomando, Payne, Weber, Sturgill: "Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 18, pp. 6940-3, (1989) (PubMed).

Synonyms and alternative names related to FES

FES proto-oncogene, tyrosine kinase (FES), FES proto-oncogene, tyrosine kinase (Fes), feline sarcoma oncogene (Fes), FES proto-oncogene, tyrosine kinase (fes), AI586313, BB137047, c-fes, c-fps, FES, FPS, RGD1564385

Protein level used designations for FES

  • Oncogene FES, feline sarcoma virus
  • feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog
  • feline sarcoma/Fujinami avian sarcoma oncogene homolog
  • p93c-fes
  • proto-oncogene c-Fes
  • proto-oncogene c-Fps
  • proto-oncogene tyrosine-protein kinase Fes/Fps
  • tyrosine-protein kinase Fes/Fps
  • V-FES feline sarcoma viral/V-FPS fujinami avian sarcoma viral oncogene homolog
  • c-fes proto-oncogene protein
  • feline sarcoma viral (v-fes) oncogene
  • v-fps oncogene homolog
  • tyrosine kinase Fps/Fes
  • feline sarcoma oncogene
  • c-fps proto oncogene
  • tyrosine-protein kinase Fes/Fps-like
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