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FERMT3 产品

(Fermitin Family Member 3 (FERMT3))

Categories

Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010].

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Featured FERMT3 Categories

FERMT3 抗体

High quality antibodies with extensive validation data.

FERMT3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

FERMT3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FERMT3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (2)
Cat. No. ABIN529478
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1501989
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN462492
Quantity 0.05 mg
Datasheet Datasheet

Recommended FERMT3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966703
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973513
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1133173
Quantity 96 tests
Datasheet Datasheet

Recommended FERMT3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353965
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096284
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2721017
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our FERMT3 Products

Feng, Li, Yau, Lee, Tang, Xue, Zhou, Lim, Cornvik, Ruedl, Shochat, Tan: "Kindlin-3 mediates integrin ?L?2 outside-in signaling, and it interacts with scaffold protein receptor for activated-C kinase 1 (RACK1)." in: The Journal of biological chemistry, Vol. 287, Issue 14, pp. 10714-26, (2012) (PubMed).

Svensson, Howarth, McDowall, Patzak, Evans, Ussar, Moser, Metin, Fried, Tomlinson, Hogg: "Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation." in: Nature medicine, Vol. 15, Issue 3, pp. 306-12, (2009) (PubMed).

Synonyms and alternative names related to FERMT3

fermitin family member 3 (Fermt3), fermitin family member 3 L homeolog (fermt3.L), fermitin family member 3 (fermt3), fermitin family member 3 (FERMT3), fermitin family member 3b (fermt3b), C79673, KIND3, Kindlin3, MGC69069, MGC88900, MIG-2, MIG2B, RGD1310168, UNC112C, URP2, URP2SF, zgc:64101

Protein level used designations for FERMT3

  • fermitin family homolog 3
  • unc-112-related protein 2
  • fermitin family member 3
  • MIG2-like protein
  • UNC-112 related protein 2
  • kindlin 3
  • kindlin-3
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