FERMT3 产品
(Fermitin Family Member 3 (FERMT3))
Categories
Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010].
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Featured FERMT3 Categories
FERMT3 抗体
High quality antibodies with extensive validation data.
FERMT3 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
FERMT3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FERMT3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (2)
Cat. No.
ABIN529478
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN1501989
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN462492
Quantity
0.05 mg
Datasheet
Datasheet
Recommended FERMT3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966703
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6973513
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1133173
Quantity
96 tests
Datasheet
Datasheet
Recommended FERMT3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353965
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3096284
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2721017
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our FERMT3 Products
: "Kindlin-3 mediates integrin ?L?2 outside-in signaling, and it interacts with scaffold protein receptor for activated-C kinase 1 (RACK1)." in: The Journal of biological chemistry, Vol. 287, Issue 14, pp. 10714-26, (2012) (PubMed).: "Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation." in: Nature medicine, Vol. 15, Issue 3, pp. 306-12, (2009) (PubMed).
Synonyms and alternative names related to FERMT3
fermitin family member 3 (Fermt3), fermitin family member 3 L homeolog (fermt3.L), fermitin family member 3 (fermt3), fermitin family member 3 (FERMT3), fermitin family member 3b (fermt3b), C79673, KIND3, Kindlin3, MGC69069, MGC88900, MIG-2, MIG2B, RGD1310168, UNC112C, URP2, URP2SF, zgc:64101Protein level used designations for FERMT3
- fermitin family homolog 3
- unc-112-related protein 2
- fermitin family member 3
- MIG2-like protein
- UNC-112 related protein 2
- kindlin 3
- kindlin-3
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