FCGR3B 产品
(Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))
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The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012].
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Featured FCGR3B Categories
FCGR3B 抗体
High quality antibodies with extensive validation data.
FCGR3B ELISA试剂盒
Reliable ELISA kits for a wide range of species.
FCGR3B 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FCGR3B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
FACS, ELISA
Validations
- (4)
Cat. No.
ABIN5684131
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7426247
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7158551
Quantity
100 μg
Datasheet
Datasheet
Recommended FCGR3B ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955741
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Guinea Pig
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN776795
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rabbit
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN774840
Quantity
96 tests
Datasheet
Datasheet
Recommended FCGR3B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274600
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274593
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274601
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our FCGR3B Products
: "Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies." in: mAbs, Vol. 11, Issue 5, pp. 826-836, (2020) (PubMed).: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).
: "VISTA deficiency attenuates antibody-induced arthritis and alters macrophage gene expression in response to simulated immune complexes." in: Arthritis research & therapy, Vol. 19, Issue 1, pp. 270, (2018) (PubMed).
: "The ARE-binding protein Tristetraprolin (TTP) is a novel target and mediator of calcineurin tumor suppressing function in the skin." in: PLoS genetics, Vol. 14, Issue 5, pp. e1007366, (2018) (PubMed).
: "FcγRIIIa-Syk Co-signal Modulates CD4+ T-cell Response and Up-regulates Toll-like Receptor (TLR) Expression." in: The Journal of biological chemistry, Vol. 291, Issue 3, pp. 1368-86, (2016) (PubMed).
: "Evidence for chemokine synergy during neutrophil migration in ARDS." in: Thorax, Vol. 72, Issue 1, pp. 66-73, (2016) (PubMed).
: "Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5471-85, (2014) (PubMed).
: "An afucosylated anti-CD20 monoclonal antibody with greater antibody-dependent cellular cytotoxicity and B-cell depletion and lower complement-dependent cytotoxicity than rituximab." in: Molecular immunology, Vol. 50, Issue 3, pp. 134-41, (2012) (PubMed).
: "Immune complexes and late complement proteins trigger activation of Syk tyrosine kinase in human CD4(+) T cells." in: Clinical and experimental immunology, Vol. 167, Issue 2, pp. 235-45, (2012) (PubMed).
: "Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus." in: European journal of human genetics : EJHG, Vol. 18, Issue 9, pp. 1027-31, (2010) (PubMed).
Synonyms and alternative names related to FCGR3B
Fc fragment of IgG receptor IIIb (FCGR3B), Fc receptor, IgG, low affinity III (Fcgr3), Fc fragment of IgG receptor IIIa (FCGR3A), Fc-gamma RIII (FCGR3), CD16, CD16b, FCG3, FCGR3, FCR-10, FCRIII, FcRIII, FCRIIIbProtein level used designations for FCGR3B
- Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
- Fc-gamma receptor IIIb (CD 16)
- fc-gamma RIII
- fc-gamma RIII-beta
- fc-gamma RIIIb
- igG Fc receptor III-1
- low affinity immunoglobulin gamma Fc region receptor III-B
- Fc gamma receptor III
- Fcg receptor III
- FcgammaRIII
- fcRIII
- igG Fc receptor III
- low affinity immunoglobulin gamma Fc region receptor III
- FcgammaRIII a.1
- cytolytic trigger molecule G7
- Fc gamma RIIIa
- IgG Fc receptor III
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