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FCGR3A 蛋白

(Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
FCGR3A Protein (AA 17-208) (His-Avi Tag) FCGR3A Protein (AA 17-208) (His-Avi Tag) FCGR3A Protein (AA 17-208) (His-Avi Tag) (ABIN7274281)

FCGR3A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

FCGR3A Protein (His-Avi Tag,Biotin) FCGR3A Protein (His-Avi Tag,Biotin) FCGR3A Protein (His-Avi Tag,Biotin) (ABIN7274282)

FCGR3A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC

FCGR3A Protein (AA 17-208) (His-Avi Tag,Biotin) FCGR3A Protein (AA 17-208) (His-Avi Tag,Biotin) FCGR3A Protein (AA 17-208) (His-Avi Tag,Biotin) (ABIN7536872)

FCGR3A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % by SEC-HPLC SDS, SEC-HPLC, SPR

FCGR3A 蛋白 by Origin

Find FCGR3A 蛋白 for a variety of species such as anti-Human FCGR3A, anti-Mouse FCGR3A, anti-Rat FCGR3A. The species listed below are among those available. Click on a link to go to the corresponding products.

FCGR3A 蛋白 by Source

Here you will find FCGR3A 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

FCGR3A 蛋白 by 蛋白类型

Here you can find FCGR3A 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

FCGR3A 蛋白 by 应用范围

Find FCGR3A 蛋白 validated for a specific application such as SDS, WB, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

FCGR3A 蛋白 by 生物活性

Find FCGR3A 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular FCGR3A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274281
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274282
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7536872
Quantity 250 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1353901
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
  • (2)
Cat. No. ABIN2181078
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7321023
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6961127
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7195704
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7195697
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7195703
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7317018
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN2870739
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN2870544
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN6573507
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7504321
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FCGR3A 蛋白

de Taeye, Bentlage, Mebius, Meesters, Lissenberg-Thunnissen, Falck, Sénard, Salehi, Wuhrer, Schuurman, Labrijn, Rispens, Vidarsson: "FcγR Binding and ADCC Activity of Human IgG Allotypes." in: Frontiers in immunology, Vol. 11, pp. 740, (2020) (PubMed).

Aoyama, Hashii, Tsukimura, Osumi, Harazono, Tada, Kiyoshi, Matsuda, Ishii-Watabe: "Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies." in: mAbs, Vol. 11, Issue 5, pp. 826-836, (2020) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Zhao, Li, Wu, Li, Liu, Wang, Liu, Li, Wang: "Identification of anti-CD16a single domain antibodies and their application in bispecific antibodies." in: Cancer biology & therapy, pp. 1-9, (2019) (PubMed).

Huang, Li, Liu, Ye, Fan, Yuan, Wu, Chen, Jin, Shen, Feng, Zhang: "Structural and functional characterization of MBS301, an afucosylated bispecific anti-HER2 antibody." in: mAbs, Vol. 10, Issue 6, pp. 864-875, (2019) (PubMed).

Dakshinamurthy, Mukunda, Prasad Kodaganti, Shenoy, Natarajan, Maliwalave, Halan, Murugesan, Maity: "Charge variant analysis of proposed biosimilar to Trastuzumab." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 46, pp. 46-56, (2017) (PubMed).

Hayes, Frostell, Cosgrave, Struwe, Potter, Davey, Karlsson, Anneren, Rudd: "Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5471-85, (2014) (PubMed).

Sakamoto, Ito, Hatanaka, Soni, Mori, Sugimura: "Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9986-93, (2009) (PubMed).

Aliases for FCGR3A 蛋白

Fc fragment of IgG receptor IIIa (FCGR3A) 蛋白
Fc fragment of IgG receptor IIIa (Fcgr3a) 蛋白
CD16 蛋白
CD16A 蛋白
FCG3 蛋白
FCGR3 蛋白
Fcgr4 蛋白
FCGRIII 蛋白
FCR-10 蛋白
FCRIII 蛋白
FCRIIIA 蛋白
IGFR3 蛋白
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