FCGR2B 产品
(Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
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The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
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Featured FCGR2B Categories
FCGR2B 抗体
High quality antibodies with extensive validation data.
FCGR2B ELISA试剂盒
Reliable ELISA kits for a wide range of species.
FCGR2B 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FCGR2B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey, Mouse
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
- (6)
Cat. No.
ABIN761411
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (5)
Cat. No.
ABIN560858
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (5)
Cat. No.
ABIN185377
Quantity
100 μg
Datasheet
Datasheet
Recommended FCGR2B ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955739
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1889450
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN2859328
Quantity
96 tests
Datasheet
Datasheet
Recommended FCGR2B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274288
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274290
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274287
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our FCGR2B Products
: "Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies." in: mAbs, Vol. 11, Issue 5, pp. 826-836, (2020) (PubMed).: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).
: "Live simian immunodeficiency virus vaccine correlate of protection: immune complex-inhibitory Fc receptor interactions that reduce target cell availability." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 6, pp. 3126-33, (2014) (PubMed).
: "Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5471-85, (2014) (PubMed).
: "Human FcγRII cytoplasmic domains differentially influence antibody-mediated dengue virus infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 11, pp. 5659-65, (2013) (PubMed).
: "Anti-peptidoglycan antibodies and Fcγ receptors are the key mediators of inflammation in Gram-positive sepsis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 5, pp. 2423-31, (2012) (PubMed).
: "Interaction with Fc?RIIB is critical for the agonistic activity of anti-CD40 monoclonal antibody." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 4, pp. 1754-63, (2011) (PubMed).
: "Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9986-93, (2009) (PubMed).
: "Restoration of tolerance in lupus by targeted inhibitory receptor expression." in: Science (New York, N.Y.), Vol. 307, Issue 5709, pp. 590-3, (2005) (PubMed).
Synonyms and alternative names related to FCGR2B
Fc fragment of IgG receptor IIb (FCGR2B), Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B), Fc receptor, IgG, low affinity IIb (Fcgr2b), Fc fragment of IgG receptor IIb (Fcgr2b), low affinity immunoglobulin gamma Fc region receptor II (LOC100856270), AI528646, CD32, CD32B, F630109E10Rik, FCG2, FCGR2, Fcgr2, Fcgr2a, FCGR2B, FcgRII, Fcr-2, Fcr-3, FCRII, FcRII, Fc[g]RII, IGFR2, Ly-17, Ly-m20, LyM-1, Lym-1Protein level used designations for FCGR2B
- CDw32
- Fc fragment of IgG, low affinity II, receptor for (CD32)
- Fc fragment of IgG, low affinity IIb, receptor for (CD32)
- Fc gamma RIIb
- fc-gamma RII-b
- fc-gamma-RIIb
- fcRII-b
- igG Fc receptor II-b
- low affinity immunoglobulin gamma Fc region receptor II-b
- Fc fragment of IgG, low affinity IIb, receptor (CD32)
- Fc fragment of IgG, low affinity IIb, receptor
- IgG Fc gamma receptor II
- fc-gamma RII
- fcRII
- igG Fc receptor II
- low affinity immunoglobulin gamma Fc region receptor II
- Fc gamma RIIB
- Fc-gamma-RII
- FcgammaRIIB
- fc gamma receptor IIB
- fc-gamma-RIIB
- igG Fc receptor II beta
- lymphocyte antigen 17
- FC-gamma RII
- Fc receptor, IgG, low affinity IIb
- low affinity immunoglobulin gamma FC region receptor II
- Fc-gamma RII
- IgG Fc receptor II
- Fc gamma receptor II
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