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FCGR2A 产品

(Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))

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This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008].

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Featured FCGR2A Categories

FCGR2A 抗体

High quality antibodies with extensive validation data.

FCGR2A ELISA试剂盒

Reliable ELISA kits for a wide range of species.

FCGR2A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FCGR2A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC, IP, IHC (p)
Validations
  • (14)
Cat. No. ABIN1497259
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, IHC, IP, IHC (p)
Validations
  • (9)
Cat. No. ABIN1497264
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC
Validations
  • (5)
Cat. No. ABIN7158537
Quantity 100 μg
Datasheet Datasheet

Recommended FCGR2A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951603
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1743244
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774149
Quantity 96 tests
Datasheet Datasheet

Recommended FCGR2A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274277
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274283
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274284
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FCGR2A Products

Wang, Peng, Wang, Jiao, Wang, Huang, Shan, Jiang, Li, Gu, Chen, Hu, Yao, Min, Zhang, Chen, Gao, Tang, Li, Wang, Wang, Zhang, Chen, Gui, Yuan, Liu: "Characterization of neutralizing antibody with prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus monkeys." in: Nature communications, Vol. 11, Issue 1, pp. 5752, (2020) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Henze, Luong, Boehme, Masyout, Schneider, Brachs, Lang, Pieske, Pasch, Eckardt, Voelkl, Alesutan: "Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells." in: Aging, Vol. 11, Issue 15, pp. 5445-5462, (2019) (PubMed).

Tharinger, Rebbapragada, Samuel, Novikov, Nguyen, Jordan, Frey, Pflanz: "Antibody-dependent and antibody-independent uptake of HBsAg across human leucocyte subsets is similar between individuals with chronic hepatitis B virus infection and healthy donors." in: Journal of viral hepatitis, Vol. 24, Issue 6, pp. 506-513, (2018) (PubMed).

Qureshi, Rowley, Junker, Peters, Crilly, Compson, Eddleston, Björkelund, Greenslade, Parkinson, Davies, Griffin, Pither, Cain, Christodoulou, Staelens, Ward, Tibbitts, Kiessling, Smith, Brennan et al.: "Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions. ..." in: Scientific reports, Vol. 7, Issue 1, pp. 17049, (2018) (PubMed).

Kuzmina, Younan, Gilchuk, Santos, Flyak, Ilinykh, Huang, Lubaki, Ramanathan, Crowe, Bukreyev: "Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors." in: Cell reports, Vol. 24, Issue 7, pp. 1802-1815.e5, (2018) (PubMed).

McWilliams, Mele, Cheney, Timmerman, Fiazuddin, Strattan, Mo, Byrd, Muthusamy, Awan: "Therapeutic CD94/NKG2A blockade improves natural killer cell dysfunction in chronic lymphocytic leukemia." in: Oncoimmunology, Vol. 5, Issue 10, pp. e1226720, (2016) (PubMed).

Vaughan, Chan, Klein, Glennie, Beers, Cragg: "Activatory and inhibitory Fcγ receptors augment rituximab-mediated internalization of CD20 independent of signaling via the cytoplasmic domain." in: The Journal of biological chemistry, Vol. 290, Issue 9, pp. 5424-37, (2015) (PubMed).

Tjiam, Taylor, Morshidi, Sariputra, Burrows, Martin, Deeks, Tan, Lee, Fernandez, French: "Viremic HIV Controllers Exhibit High Plasmacytoid Dendritic Cell-Reactive Opsonophagocytic IgG Antibody Responses against HIV-1 p24 Associated with Greater Antibody Isotype Diversification." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 11, pp. 5320-8, (2015) (PubMed).

Hayes, Frostell, Cosgrave, Struwe, Potter, Davey, Karlsson, Anneren, Rudd: "Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5471-85, (2014) (PubMed).

Synonyms and alternative names related to FCGR2A

Fc fragment of IgG receptor IIa (FCGR2A), CD32, CD32A, CD32a, CDw32, FCG2, FcGR, FCGR2, FCGR2A1, IGFR2

Protein level used designations for FCGR2A

  • Immunoglobulin G Fc receptor II
  • fc-gamma RII-a
  • fc-gamma-RIIa
  • fcRII-a
  • igG Fc receptor II-a
  • low affinity immunoglobulin gamma Fc region receptor II-a
  • Fc fragment of IgG, low affinity IIa, receptor for (CD32)
  • Fc gamma receptor IIa
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