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Fc Receptor, IgG, Low Affinity IV 抗体

(Fc Receptor, IgG, Low Affinity IV (FCGR4))

Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578). Also acts as a receptor for the Fc region of immunoglobulin epsilon (PubMed:17558411, PubMed:18949059). Binds with intermediate affinity to both IgG2a and IgG2b (PubMed:16039578, PubMed:17558411, PubMed:19795417). Can bind to IgG2a and IgG2b monomers (PubMed:18949059). Does not display binding to IgG1 or IgG3 (PubMed:16039578). Mediates neutrophil activation by IgG complexes redundantly with Fcgr3 (PubMed:18097064). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (PubMed:25824719). Binds with low affinity to both the a and b allotypes of IgE (PubMed:18949059). Has also been shown to bind to IgE allotype a only but not to allotype b (PubMed:17558411). Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes (PubMed:18949059). Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions (PubMed:17558411, PubMed:18949059). {ECO:0000269|PubMed:16039578, ECO:0000269|PubMed:17558411, ECO:0000269|PubMed:18097064, ECO:0000269|PubMed:18949059, ECO:0000269|PubMed:19795417, ECO:0000269|PubMed:25824719}.

FCGR4 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal AT137 FITC

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FCGR4 适用: 小鼠 FACS, IHC (fro) 宿主: 大鼠 Monoclonal AT137 unconjugated

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Fc Receptor, IgG, Low Affinity IV 抗体 by 适用

Find Fc Receptor, IgG, Low Affinity IV 抗体 for a variety of species such as anti-Mouse Fc Receptor, IgG, Low Affinity IV. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find Fc Receptor, IgG, Low Affinity IV 抗体 validated for a specific application such as FACS, IHC (fro). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find Fc Receptor, IgG, Low Affinity IV 抗体 with a specific conjugate such as FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Fc Receptor, IgG, Low Affinity IV 抗体

Product

Reactivity

Application

Validations

Cat. No.

Quantity

Datasheet

anti-Fc Receptor, IgG, Low Affinity IV (FCGR4) 抗体 (FITC)

Reactivity Mouse

Application FACS

Validations

Cat. No. ABIN2478684

Quantity 0.1 mg

Datasheet Datasheet

anti-Fc Receptor, IgG, Low Affinity IV (FCGR4) 抗体

Reactivity Mouse

Application FACS, IHC (fro)

Validations

Cat. No. ABIN2478683

Quantity 0.25 mg

Datasheet Datasheet

Latest Publications for our Fc Receptor, IgG, Low Affinity IV 抗体

Patel, Kim, Theodros, Tam, Velarde, Kochel, Francica, Nirschl, Ghasemzadeh, Mathios, Harris-Bookman, Jackson, Jackson, Ye, Tran, Tyler, Coric, Selby, Brem, Drake, Pardoll, Lim: "Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma." in: Journal for immunotherapy of cancer, Vol. 4, pp. 28, (2016) (PubMed).

White, Chan, Roghanian, French, Mockridge, Tutt, Dixon, Ajona, Verbeek, Al-Shamkhani, Cragg, Beers, Glennie: "Interaction with Fc?RIIB is critical for the agonistic activity of anti-CD40 monoclonal antibody." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 4, pp. 1754-63, (2011) (PubMed).

Aliases for Fc Receptor, IgG, Low Affinity IV 抗体

Fc receptor, IgG, low affinity IV (Fcgr4) 抗体
4833442P21Rik 抗体
CD16-2 抗体
FcgammaRIV 抗体
Fcgr3a 抗体
FcgRIV 抗体
Fcrl3 抗体

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Popular Fc Receptor, IgG, Low Affinity IV 抗体

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Aliases for Fc Receptor, IgG, Low Affinity IV 抗体

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