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FBXW7 蛋白

(F-Box and WD Repeat Domain Containing 7 (FBXW7))
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class\; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012].
FBXW7 Protein (AA 599-707) (GST tag) FBXW7 Protein (AA 599-707) (GST tag) FBXW7 Protein (AA 599-707) (GST tag) (ABIN1353879)

FBXW7 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

FBXW7 Protein (AA 1-553) (GST tag) FBXW7 Protein (AA 1-553) (GST tag) FBXW7 Protein (AA 1-553) (GST tag) (ABIN1990130)

FBXW7 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

FBXW7 Protein (AA 1-707) (Strep Tag) (ABIN3092548)

FBXW7 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

FBXW7 蛋白 by Origin

Find FBXW7 蛋白 for a variety of species such as anti-Human FBXW7. The species listed below are among those available. Click on a link to go to the corresponding products.

FBXW7 蛋白 by Source

Here you will find FBXW7 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

FBXW7 蛋白 by 蛋白类型

Here you can find FBXW7 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

FBXW7 蛋白 by 应用范围

Find FBXW7 蛋白 validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular FBXW7 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353879
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1990130
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092548
Quantity 1 mg
Datasheet Datasheet

Aliases for FBXW7 蛋白

F-box and WD repeat domain containing 7 (Fbxw7) 蛋白
F-box and WD repeat domain containing 7 (FBXW7) 蛋白
F-box and WD repeat domain containing 7 (fbxw7) 蛋白
F-box and WD-40 domain protein 7 (Fbxw7) 蛋白
1110001A17Rik 蛋白
AGO 蛋白
cdc4 蛋白
CDC4 蛋白
Cdc4 蛋白
FBW6 蛋白
FBW7 蛋白
Fbw7 蛋白
Fbwd6 蛋白
FBX30 蛋白
Fbx30 蛋白
FBXO30 蛋白
Fbxo30 蛋白
FBXW6 蛋白
Fbxw6 蛋白
hAgo 蛋白
hCdc4 蛋白
SEL-10 蛋白
SEL10 蛋白
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