FBXW5 产品
(F-Box and WD Repeat Domain Containing 5 (FBXW5))
Categories
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq, Jul 2008].
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Featured FBXW5 Categories
FBXW5 抗体
High quality antibodies with extensive validation data.
FBXW5 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
FBXW5 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FBXW5 抗体
Product
Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
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- (3)
Cat. No.
ABIN7152505
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
- (1)
Cat. No.
ABIN1881341
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
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- (1)
Cat. No.
ABIN527070
Quantity
50 μg
Datasheet
Datasheet
Recommended FBXW5 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1743137
Quantity
96 tests
Datasheet
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Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1774042
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Validations
Cat. No.
ABIN1769146
Quantity
96 tests
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Recommended FBXW5 蛋白
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Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353877
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353875
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092547
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our FBXW5 Products
: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).: "An F-box protein, FBXW5, negatively regulates TAK1 MAP3K in the IL-1beta signaling pathway." in: Biochemical and biophysical research communications, Vol. 381, Issue 3, pp. 412-7, (2009) (PubMed).
: "WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase." in: Genes & development, Vol. 22, Issue 7, pp. 866-71, (2008) (PubMed).
: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, (2004) (PubMed).
Synonyms and alternative names related to FBXW5
F-box and WD repeat domain containing 5 (FBXW5), F-box and WD repeat domain containing 5 (Fbxw5), F-box and WD-40 domain protein 5 (Fbxw5), AI159739, Fbw5Protein level used designations for FBXW5
- F-box and WD-40 domain protein 5
- F-box/WD repeat-containing protein 5
- F-box and WD-40 domain-containing protein 5
- WD repeat-containing F-box protein FBW5
- F-box protein Fbw5
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