Fascin 产品
(Fascin (FSCN1))
Categories
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011].
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Featured Fascin Categories
Fascin 抗体
High quality antibodies with extensive validation data.
Fascin ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Fascin 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Fascin 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, FACS, IF, StM
Validations
- (7)
Cat. No.
ABIN6940607
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC, FACS, IF, StM
Validations
- (6)
Cat. No.
ABIN6940609
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (5)
Cat. No.
ABIN728293
Quantity
100 μL
Datasheet
Datasheet
Recommended Fascin ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955706
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1133025
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1133026
Quantity
96 tests
Datasheet
Datasheet
Recommended Fascin 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122887
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1989775
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7394765
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Fascin Products
: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).: "Clinical significance of fascin-1 and laminin-5 in non-small cell lung cancer." in: Genetics and molecular research : GMR, Vol. 16, Issue 2, (2017) (PubMed).
: "Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway." in: Stem cells (Dayton, Ohio), Vol. 34, Issue 12, pp. 2799-2813, (2016) (PubMed).
: "The retinoic acid-metabolizing enzyme CYP26A1 upregulates fascin and promotes the malignant behavior of breast carcinoma cells." in: Oncology reports, Vol. 34, Issue 2, pp. 850-8, (2015) (PubMed).
: "Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors." in: PLoS ONE, Vol. 9, Issue 1, pp. e83995, (2014) (PubMed).
: "Differential associations of circulating peroxiredoxins levels with indicators of glycemic control in type 2 diabetes mellitus." in: European review for medical and pharmacological sciences, Vol. 18, Issue 5, pp. 710-6, (2014) (PubMed).
: "Overexpression of FOXM1 is associated with metastases of nasopharyngeal carcinoma." in: Upsala journal of medical sciences, Vol. 119, Issue 4, pp. 324-32, (2014) (PubMed).
: "Migrastatin analogues inhibit canine mammary cancer cell migration and invasion." in: PLoS ONE, Vol. 8, Issue 10, pp. e76789, (2013) (PubMed).
: "Serological investigation of the clinical significance of fascin in non-small-cell lung cancer." in: Lung cancer (Amsterdam, Netherlands), Vol. 82, Issue 2, pp. 346-52, (2013) (PubMed).
: "Hyaluronic acid-dependent protection in H9C2 cardiomyocytes: a cell model of heart ischemia-reperfusion injury and treatment." in: Toxicology, Vol. 303, pp. 54-71, (2013) (PubMed).
Synonyms and alternative names related to Fascin
singed (sn), fascin actin-bundling protein 1 (fscn1), fascin actin-bundling protein 1a (fscn1a), fascin actin-bundling protein 1 (Fscn1), fascin actin-bundling protein 1 L homeolog (fscn1.L), fascin actin-bundling protein 1 (FSCN1), AI663989, CG1536, CG15331, CG32858, Dmel\\CG32858, Fan1, FAN1, Fascin, fascin, fascin-1, fs(1)A1057, fs(1)K418, fs(1)K473, fs(1)K743, fs(1)K1421, fs(1)M45, fscn, fscn1, HSN, MGC75811, p55, sb:cb589, SN, Sn, snl, SNL, zgc:153632Protein level used designations for Fascin
- CG32858-PA
- CG32858-PB
- CG32858-PD
- CG32858-PE
- CG32858-PF
- CG32858-PG
- fascin
- sn-PA
- sn-PB
- sn-PD
- sn-PE
- sn-PF
- sn-PG
- fascin-1
- fascin 1
- singed-like protein
- 55 kDa actin-bundling protein
- singed-like (fascin homolog, sea urchin)
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- FANCE
- FANCD2
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- Fascin 2
- Fascin 3
- FASL
- FasR
- FASTK
- FASTKD1
- FASTKD2
- FASTKD3
- FASTKD5
- FAT Atypical Cadherin 2
- Fat Storage-Inducing Transmembrane Protein 2
- FAT1
- FAT3
- FAT4
- FATE1
- Fatty Acid Binding Protein
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- Fatty Acid Desaturase 2
- Fatty Acid Synthase
- Fatty Acid/Retinol Binding Protein Family Member (Far-1)
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