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Fascin 2 产品

(Fascin 2 (FSCN2))
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured Fascin 2 Categories

Fascin 2 抗体

High quality antibodies with extensive validation data.

Fascin 2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Fascin 2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Fascin 2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7438274
Quantity 100 μL
Datasheet Datasheet
Reactivity Guinea Pig, Human, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (4)
  • (1)
Cat. No. ABIN6746674
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application ELISA, IHC
Validations
  • (3)
  • (1)
Cat. No. ABIN334397
Quantity 100 μg
Datasheet Datasheet

Recommended Fascin 2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966655
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1133028
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1133027
Quantity 96 tests
Datasheet Datasheet

Recommended Fascin 2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398086
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401347
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401350
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Fascin 2 Products

Burns, Kelly, Hoa, Morell, Kelley: "Single-cell RNA-Seq resolves cellular complexity in sensory organs from the neonatal inner ear." in: Nature communications, Vol. 6, pp. 8557, (2015) (PubMed).

Shin, Krey, Hassan, Metlagel, Tauscher, Pagana, Sherman, Jeffery, Spinelli, Zhao, Wilmarth, Choi, David, Auer, Barr-Gillespie: "Molecular architecture of the chick vestibular hair bundle." in: Nature neuroscience, Vol. 16, Issue 3, pp. 365-74, (2013) (PubMed).

Ramakrishnan, Drescher, Khan, Hatfield, Drescher: "HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2." in: The Journal of biological chemistry, Vol. 287, Issue 45, pp. 37628-46, (2012) (PubMed).

Shin, Longo-Guess, Gagnon, Saylor, Dumont, Spinelli, Pagana, Wilmarth, David, Gillespie, Johnson: "The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 29, pp. 9683-94, (2010) (PubMed).

Vignjevic, Kojima, Aratyn, Danciu, Svitkina, Borisy: "Role of fascin in filopodial protrusion." in: The Journal of cell biology, Vol. 174, Issue 6, pp. 863-75, (2006) (PubMed).

Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

Henglein, Chenivesse, Wang, Eick, Bréchot: "Structure and cell cycle-regulated transcription of the human cyclin A gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 12, pp. 5490-4, (1994) (PubMed).

Pines, Hunter: "The differential localization of human cyclins A and B is due to a cytoplasmic retention signal in cyclin B." in: The EMBO journal, Vol. 13, Issue 16, pp. 3772-81, (1994) (PubMed).

Pines: "Cyclins and cyclin-dependent kinases: take your partners." in: Trends in biochemical sciences, Vol. 18, Issue 6, pp. 195-7, (1993) (PubMed).

Koretz, Sugarbaker: "Diagnosis and management of colorectal cancer." in: Comprehensive therapy, Vol. 13, Issue 6, pp. 40-7, (1987) (PubMed).

Synonyms and alternative names related to Fascin 2

fascin actin-bundling protein 2, retinal (FSCN2), fascin actin-bundling protein 1 (FSCN1), fascin actin-bundling protein 2 (Fscn2), fascin actin-bundling protein 2, retinal (Fscn2), A930022G03, ahl8, C630046B20Rik, fascin-2, RFSN, RP30

Protein level used designations for Fascin 2

  • fascin-2
  • putative fascin 1
  • retinal fascin
  • fascin 2, retinal
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