FAP 产品
(Fibroblast Activation Protein, alpha (FAP))
Categories
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. [provided by RefSeq, Jul 2008].
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Featured FAP Categories
FAP 抗体
High quality antibodies with extensive validation data.
FAP ELISA试剂盒
Reliable ELISA kits for a wide range of species.
FAP 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FAP 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (4)
- (5)
Cat. No.
ABIN560844
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (6)
Cat. No.
ABIN7193479
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7434938
Quantity
100 μL
Datasheet
Datasheet
Recommended FAP ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955802
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955800
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955801
Quantity
96 tests
Datasheet
Datasheet
Recommended FAP 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274584
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274585
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274586
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our FAP Products
: "Exploring Metabolic Configurations of Single Cells within Complex Tissue Microenvironments." in: Cell metabolism, Vol. 26, Issue 5, pp. 788-800.e6, (2017) (PubMed).: "TNF-α promotes breast cancer cell migration and enhances the concentration of membrane-associated proteases in lipid rafts." in: Cellular oncology (Dordrecht), Vol. 39, Issue 4, pp. 353-63, (2017) (PubMed).
: "Enhanced Antitumor Activity of EGFP-EGF1-Conjugated Nanoparticles by a Multitargeting Strategy." in: ACS applied materials & interfaces, Vol. 8, Issue 14, pp. 8918-27, (2016) (PubMed).
: "Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability." in: Nature communications, Vol. 7, pp. 11853, (2016) (PubMed).
: "Growth differentiation factor 15 contributes to cancer-associated fibroblasts-mediated chemo-protection of AML cells." in: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 147, (2016) (PubMed).
: "FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling." in: Cancer research, Vol. 76, Issue 14, pp. 4124-35, (2016) (PubMed).
: "Extracellular Hsp90 mediates an NF-?B dependent inflammatory stromal program: implications for the prostate tumor microenvironment." in: The Prostate, Vol. 74, Issue 4, pp. 395-407, (2014) (PubMed).
: "Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activation." in: PLoS ONE, Vol. 9, Issue 2, pp. e88772, (2014) (PubMed).
: "Protumorigenic effects of Snail-expression fibroblasts on colon cancer cells." in: International journal of cancer, Vol. 134, Issue 12, pp. 2984-90, (2014) (PubMed).
: "Cancer-associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients." in: Cancer science, Vol. 104, Issue 4, pp. 437-44, (2013) (PubMed).
Synonyms and alternative names related to FAP
fibroblast activation protein (Fap), fibroblast activation protein alpha L homeolog (fap.L), fibroblast activation protein alpha (FAP), fibroblast activation protein, alpha (Fap), fibroblast activation protein alpha (fap), prolyl endopeptidase FAP (LOC100547273), fibroblast activation protein alpha (Fap), dppiv, DPPIV, FAP, fap-A, fapa, FAPA, gene 13, sepraseProtein level used designations for FAP
- fibroblast activation protein alpha
- integral membrane serine protease
- seprase
- fibroblast activation protein, alpha
- fibroblast activation protein, alpha subunit
- gene 13
- 170 kDa melanoma membrane-bound gelatinase
- seprase-like
- prolyl endopeptidase FAP
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- Family with Sequence Similarity 92, Member A1
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