FANCD2 抗体
(Fanconi Anemia, Complementation Group D2 (FANCD2))
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
FANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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Latest Publications for our FANCD2 抗体
: "Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia pathway genes in zebrafish revealed their roles in growth, sexual development and fertility." in: PLoS genetics, Vol. 14, Issue 12, pp. e1007821, (2019) (PubMed).: "Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia." in: Nature communications, Vol. 9, Issue 1, pp. 3915, (2019) (PubMed).
: "Mammalian INO80 chromatin remodeler cooperates with FANCM to mediate DNA interstrand crosslink-induced checkpoint activation and repair." in: DNA repair, Vol. 74, pp. 38-50, (2019) (PubMed).
: "Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability." in: Nucleic acids research, (2019) (PubMed).
: "Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance. ..." in: EMBO molecular medicine, (2019) (PubMed).
: "Remodeling of Interstrand Crosslink Proximal Replisomes Is Dependent on ATR, FANCM, and FANCD2." in: Cell reports, Vol. 27, Issue 6, pp. 1794-1808.e5, (2019) (PubMed).
: "Dicer prevents genome instability in response to replication stress." in: Oncotarget, Vol. 10, Issue 43, pp. 4407-4423, (2019) (PubMed).
: "FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2." in: Nature communications, Vol. 8, Issue 1, pp. 1073, (2018) (PubMed).
: "Fanconi anemia core complex-dependent HES1 mono-ubiquitination regulates its transcriptional activity." in: BMC research notes, Vol. 11, Issue 1, pp. 138, (2018) (PubMed).
: "Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2." in: Molecular cell, Vol. 71, Issue 1, pp. 25-41.e6, (2018) (PubMed).
Aliases for FANCD2 抗体
Fanconi anemia complementation group D2 (FANCD2) 抗体CG17269 gene product from transcript CG17269-RA (Fancd2) 抗体
Fanconi anemia group D2 protein (LOC100455970) 抗体
Fanconi anemia complementation group D2 (fancd2) 抗体
Fanconi anemia, complementation group D2 (fancd2) 抗体
Fanconi anemia complementation group D2 L homeolog (fancd2.L) 抗体
Fanconi anemia, complementation group D2 (FANCD2) 抗体
Fanconi anemia, complementation group D2 (Fancd2) 抗体
2410150O07Rik 抗体
AU015151 抗体
BB137857 抗体
CG17269 抗体
CG31192 抗体
CG31194 抗体
Dmel\\CG17269 抗体
dmFANCD2 抗体
FA-D2 抗体
FA4 抗体
FACD 抗体
FAD 抗体
FAD2 抗体
FANCD 抗体
FANCD2 抗体
xfancd2 抗体
您还需要查找其他产品吗？
- FANCC 抗体
- FANCB 抗体
- FANCA 抗体
- FAN1 抗体
- Family with Sequence Similarity 92, Member A1 抗体
- Family with Sequence Similarity 58, Member B 抗体
- Family with Sequence Similarity 50, Member A 抗体
- Family with Sequence Similarity 46, Member B 抗体
- Family with Sequence Similarity 212, Member A 抗体
- FAM9B 抗体
- FAM98A 抗体
- FAM96B 抗体
- FAM96A 抗体
- FAM90A1 抗体
- FAM8A1 抗体
- FAM84A 抗体
- FAM83H 抗体
- FAM83D 抗体
- FAM82B 抗体
- FAM76A 抗体
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