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FANCC 产品

(Fanconi Anemia, Complementation Group C (FANCC))

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The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq, Jul 2008].

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Featured FANCC Categories

FANCC 抗体

High quality antibodies with extensive validation data.

FANCC 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FANCC 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN3022594
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (5)
Cat. No. ABIN947854
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, IHC (p), ICC
Validations
  • (1)
  • (4)
Cat. No. ABIN2854743
Quantity 100 μL
Datasheet Datasheet

Recommended FANCC ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228398
Quantity 96 tests
Datasheet Datasheet

Recommended FANCC 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353626
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353628
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3134338
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our FANCC Products

Pan, Wang, Chen, Ding, Jiang, Gao, Mo, Huang, Lou, Cao: "Deleterious Mutations in DNA Repair Gene FANCC Exist in BRCA1/2-Negative Chinese Familial Breast and/or Ovarian Cancer Patients." in: Frontiers in oncology, Vol. 9, pp. 169, (2019) (PubMed).

Yung, Tilgner, Ledran, Habibollah, Neganova, Singhapol, Saretzki, Stojkovic, Armstrong, Przyborski, Lako: "Brief report: human pluripotent stem cell models of fanconi anemia deficiency reveal an important role for fanconi anemia proteins in cellular reprogramming and survival of hematopoietic progenitors." in: Stem cells (Dayton, Ohio), Vol. 31, Issue 5, pp. 1022-9, (2013) (PubMed).

Moeller, Yordy, Williams, Giri, Raju, Molkentine, Byers, Heymach, Story, Lee, Sturgis, Weber, Garden, Ang, Schwartz: "DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 7, pp. 2035-43, (2011) (PubMed).

Freie, Ciccone, Li, Plett, Orschell, Srour, Hanenberg, Schindler, Lee, Clapp: "A role for the Fanconi anemia C protein in maintaining the DNA damage-induced G2 checkpoint." in: The Journal of biological chemistry, Vol. 279, Issue 49, pp. 50986-93, (2004) (PubMed).

Synonyms and alternative names related to FANCC

Fanconi anemia complementation group C (FANCC), Fanconi anemia, complementation group C (fancc), Fanconi anemia complementation group C L homeolog (fancc.L), Fanconi anemia, complementation group C (Fancc), BB116513, fa3, FA3, fac, FAC, facc, FACC, Facc, FANCC, zgc:154105

Protein level used designations for FANCC

  • Fanconi anemia, complementation group C protein
  • Fanconi anemia C
  • Fanconi anemia, complementation group C
  • fanconi anemia group C protein-like
  • Fanconi anemia group C protein-like
  • Fanconi anemia group C protein
  • Fanconi anemia group C protein homolog
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