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FAM84A 产品

(Family with Sequence Similarity 84, Member A (FAM84A))

Categories

Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Has in vitro ubiquitin ligase activity in presence of NDNL2. Is involved in positive regulation of response to DNA damage stimulus.

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Featured FAM84A Categories

FAM84A 抗体

High quality antibodies with extensive validation data.

FAM84A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FAM84A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN566864
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
  • (2)
Cat. No. ABIN1386304
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB, IHC
Validations
  • (2)
Cat. No. ABIN7248623
Quantity 200 μL
Datasheet Datasheet

Recommended FAM84A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122885
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353598
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2727638
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our FAM84A Products

Brändle, Obermeier, Senel, Bruder, Mentele, Khademi, Olsson, Tumani, Kristoferitsch, Lottspeich, Wekerle, Hohlfeld, Dornmair: "Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 28, pp. 7864-9, (2016) (PubMed).

Wang, Xu, Qin, Wang, Ma, Luo, Zhang: "Myocardin-related transcription factor-A is a key regulator in retinoic acid-induced neural-like differentiation of adult bone marrow-derived mesenchymal stem cells." in: Gene, Vol. 523, Issue 2, pp. 178-86, (2013) (PubMed).

Synonyms and alternative names related to FAM84A

family with sequence similarity 84, member A (Fam84a), family with sequence similarity 84 member A (FAM84A), family with sequence similarity 84, member A (fam84a), family with sequence similarity 84 member A (Fam84a), 2310003N02Rik, 4731402F03Rik, AW125753, Nse1, NSE1, PP11517, RGD1305779, zgc:63724

Protein level used designations for FAM84A

  • protein FAM84A
  • neurologic sensory protein 1
  • neurological/sensory 1
  • family with sequence similarity 84, member A
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