FAK 产品
(PTK2 Protein tyrosine Kinase 2 (PTK2))
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This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010].
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Featured FAK Categories
FAK 抗体
High quality antibodies with extensive validation data.
FAK ELISA试剂盒
Reliable ELISA kits for a wide range of species.
FAK 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FAK 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
- (8)
Cat. No.
ABIN6256730
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (1)
- (7)
Cat. No.
ABIN6146423
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7439699
Quantity
100 μL
Datasheet
Datasheet
Recommended FAK ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958990
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969779
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962403
Quantity
96 tests
Datasheet
Datasheet
Recommended FAK 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
Cat. No.
ABIN1316775
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124708
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316777
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our FAK Products
: "Role and Regulation of Mechanotransductive HIF-1α Stabilisation in Periodontal Ligament Fibroblasts." in: International journal of molecular sciences, Vol. 21, Issue 24, (2021) (PubMed).: "Phosphorylation of EphA2 receptor and vasculogenic mimicry is an indicator of poor prognosis in invasive carcinoma of the breast." in: Breast cancer research and treatment, Vol. 179, Issue 2, pp. 359-370, (2020) (PubMed).
: "ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP." in: FEBS letters, Vol. 592, Issue 4, pp. 599-609, (2019) (PubMed).
: "Porcine Breast Extracellular Matrix Hydrogel for Spatial Tissue Culture." in: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).
: "Depletion of transglutaminase 2 in neurons alters expression of extracellular matrix and signal transduction genes and compromises cell viability." in: Molecular and cellular neurosciences, Vol. 86, pp. 72-80, (2018) (PubMed).
: "Down-regulating Myoferlin inhibits the vasculogenic mimicry of melanoma via decreasing MMP-2 and inducing mesenchymal-to-epithelial transition." in: Journal of cellular and molecular medicine, Vol. 22, Issue 3, pp. 1743-1754, (2018) (PubMed).
: "MFAP5 promotes tumor progression and bone metastasis by regulating ERK/MMP signaling pathways in breast cancer." in: Biochemical and biophysical research communications, Vol. 498, Issue 3, pp. 495-501, (2018) (PubMed).
: "Ovostatin 2 knockdown significantly inhibits the growth, migration, and tumorigenicity of cutaneous malignant melanoma cells." in: PLoS ONE, Vol. 13, Issue 4, pp. e0195610, (2018) (PubMed).
: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." in: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).
: "Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 175, (2018) (PubMed).
Synonyms and alternative names related to FAK
protein tyrosine kinase 2 (PTK2), protein tyrosine kinase 2 L homeolog (ptk2.L), PTK2 protein tyrosine kinase 2 (PTK2), PTK2 protein tyrosine kinase 2 (Ptk2), protein tyrosine kinase 2ab (ptk2ab), protein tyrosine kinase 2 (Ptk2), Focal adhesion kinase (Fak), CG10023, CT28129, DFAK, DFak, Dfak, DFak56, Dfak56, Dmel\\CG10023, DmFAK, FADK, Fadk, FAK, fak, FAK1, fak1a, Fak56, fak56, Fak56D, FRNK, mKIAA4203, p125FAK, pp125FAK, PPP1R71, PTK2, ptk2, ptk2a, wu:fa18c04, zgc:66114Protein level used designations for FAK
- FADK 1
- FAK-related non-kinase polypeptide
- PTK2 protein tyrosine kinase 2
- focal adhesion kinase 1
- focal adhesion kinase-related nonkinase
- protein phosphatase 1 regulatory subunit 71
- protein phosphatase 1, regulatory subunit 71
- focal adhesion kinase pp125FAK
- pp125FAK
- protein-tyrosine kinase 2
- focal adhesion kinase
- focal ashension kinase 1
- p41/p43FRNK
- faka
- protein tyrosine kinase 2.1
- CG10023-PA
- CG10023-PB
- CG10023-PC
- CG10023-PD
- CG10023-PF
- CG10023-PG
- Fak-PA
- Fak-PB
- Fak-PC
- Fak-PD
- Fak-PF
- Fak-PG
- focal adhesion kinase homolog
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