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EWSR1 蛋白

(Ewing Sarcoma Breakpoint Region 1 (EWSR1))

This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11\;22)(q24\;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. [provided by RefSeq, Jul 2009].

recommended

EWSR1 Protein (AA 358-453) (GST tag) (ABIN1353206)

EWSR1 宿主: 人宿主: 小麦胚 Recombinant AA, AP, ELISA, WB

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recommended

EWSR1 Protein (Transcript Variant EWS) (Myc-DYKDDDDK Tag) (ABIN2720598)

EWSR1 宿主: 人宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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EWSR1 蛋白 by Origin

Find EWSR1 蛋白 for a variety of species such as anti-Human EWSR1. The species listed below are among those available. Click on a link to go to the corresponding products.

EWSR1 蛋白 by Source

Here you will find EWSR1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

EWSR1 蛋白 by 蛋白类型

Here you can find EWSR1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

EWSR1 蛋白 by 应用范围

Find EWSR1 蛋白 validated for a specific application such as AP, AA, AbP, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular EWSR1 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

EWSR1 Protein (AA 358-453) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1353206

Quantity 10 μg

Datasheet Datasheet

EWSR1 Protein (Transcript Variant EWS) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2720598

Quantity 20 μg

Datasheet Datasheet

Latest Publications for our EWSR1 蛋白

Altmeyer, Neelsen, Teloni, Pozdnyakova, Pellegrino, Grøfte, Rask, Streicher, Jungmichel, Nielsen, Lukas: "Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)." in: Nature communications, Vol. 6, pp. 8088, (2015) (PubMed).

Aliases for EWSR1 蛋白

EWS RNA binding protein 1 (EWSR1) 蛋白
Ewing sarcoma breakpoint region 1 (Ewsr1) 蛋白
EWS RNA-binding protein 1 (Ewsr1) 蛋白
EWS RNA-binding protein 1a (ewsr1a) 蛋白
EWS RNA binding protein 1 (ewsr1) 蛋白
EWS RNA binding protein 1 (Ewsr1) 蛋白
EWS RNA binding protein 1 L homeolog (ewsr1.L) 蛋白
EWS RNA-binding protein 1b (ewsr1b) 蛋白
AU018891 蛋白
bK984G1.4 蛋白
DKFZp459K1116 蛋白
EWS 蛋白
Ews 蛋白
Ewsh 蛋白
EWSR1 蛋白
ewsr1 蛋白
ewsr1.S 蛋白
fb40b11 蛋白
fc04c01 蛋白
fusl 蛋白
wu:fb40b11 蛋白
wu:fb75g09 蛋白
wu:fc04c01 蛋白
zgc:55864 蛋白

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EWSR1 蛋白 by Origin

EWSR1 蛋白 by Source

EWSR1 蛋白 by 蛋白类型

EWSR1 蛋白 by 应用范围

Popular EWSR1 蛋白

Latest Publications for our EWSR1 蛋白

Aliases for EWSR1 蛋白

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