ETV1 抗体
(Ets Variant 1 (ETV1))
This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Erwing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
recommended
recommended
recommended
ETV1 抗体 by Grade
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ETV1 抗体 by 应用范围
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ETV1 抗体 by 克隆形成能力
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ETV1 抗体 by 克隆
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Validations
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Datasheet
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Application
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Datasheet
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Quantity
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Datasheet
Datasheet
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Quantity
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Datasheet
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Datasheet
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Datasheet
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Quantity
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Datasheet
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Reactivity
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Datasheet
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Latest Publications for our ETV1 抗体
: "TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions." in: Neoplasia (New York, N.Y.), Vol. 8, Issue 10, pp. 826-32, (2006) (PubMed).: "Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer." in: Science (New York, N.Y.), Vol. 310, Issue 5748, pp. 644-8, (2005) (PubMed).
: "Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity." in: Science (New York, N.Y.), Vol. 282, Issue 5392, pp. 1321-4, (1998) (PubMed).
: "Identification of a gephyrin binding motif on the glycine receptor beta subunit." in: Neuron, Vol. 15, Issue 3, pp. 563-72, (1995) (PubMed).
: "Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein." in: Neuron, Vol. 8, Issue 6, pp. 1161-70, (1992) (PubMed).
Aliases for ETV1 抗体
ETS variant 1 (etv1) 抗体ETS variant 1 (ETV1) 抗体
ets variant 1 (Etv1) 抗体
ETS variant 1 S homeolog (etv1.S) 抗体
ets variant 1 (etv1) 抗体
er81 抗体
ER81 抗体
Etsrp81 抗体
MGC75591 抗体
XER81 抗体
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