ETV1 产品
(Ets Variant 1 (ETV1))
Categories
This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Erwing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
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Featured ETV1 Categories
Recommended ETV1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN560803
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN6140327
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN969120
Quantity
100 μL
Datasheet
Datasheet
Recommended ETV1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648152
Quantity
96 tests
Datasheet
Datasheet
Recommended ETV1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353176
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3079625
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3133992
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ETV1 Products
: "TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions." in: Neoplasia (New York, N.Y.), Vol. 8, Issue 10, pp. 826-32, (2006) (PubMed).: "Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer." in: Science (New York, N.Y.), Vol. 310, Issue 5748, pp. 644-8, (2005) (PubMed).
: "Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity." in: Science (New York, N.Y.), Vol. 282, Issue 5392, pp. 1321-4, (1998) (PubMed).
: "Identification of a gephyrin binding motif on the glycine receptor beta subunit." in: Neuron, Vol. 15, Issue 3, pp. 563-72, (1995) (PubMed).
: "Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein." in: Neuron, Vol. 8, Issue 6, pp. 1161-70, (1992) (PubMed).
Synonyms and alternative names related to ETV1
ETS variant 1 (etv1), ETS variant 1 (ETV1), ets variant 1 (Etv1), ETS variant 1 S homeolog (etv1.S), ets variant 1 (etv1), er81, ER81, Etsrp81, MGC75591, XER81Protein level used designations for ETV1
- ets variant 1
- ets domain protein
- ets variant gene 1
- ETS translocation variant 1
- ets-related protein 81
- ets-related transcription factor XER81
- ets related protein 81
- ETS transcription factor Er81
- er81
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