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ESRRG 产品

(Estrogen-Related Receptor gamma (ESRRG))

Categories

This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors\; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region. [provided by RefSeq, Aug 2011].

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Featured ESRRG Categories

ESRRG 抗体

High quality antibodies with extensive validation data.

ESRRG ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ESRRG 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ESRRG 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (6)
Cat. No. ABIN1491251
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (2)
  • (4)
Cat. No. ABIN2777400
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7241249
Quantity 200 μL
Datasheet Datasheet

Recommended ESRRG ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966598
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966599
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1132341
Quantity 96 tests
Datasheet Datasheet

Recommended ESRRG 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353137
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353135
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3120769
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ESRRG Products

Song, Wang: "A conserved gene structure and expression regulation of miR-433 and miR-127 in mammals." in: PLoS ONE, Vol. 4, Issue 11, pp. e7829, (2009) (PubMed).

Song, Wang: "Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRgamma." in: Nucleic acids research, Vol. 36, Issue 18, pp. 5727-35, (2008) (PubMed).

Dufour, Wilson, Huss, Kelly, Alaynick, Downes, Evans, Blanchette, Giguère: "Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma." in: Cell metabolism, Vol. 5, Issue 5, pp. 345-56, (2007) (PubMed).

Zhang, Teng: "Interplay between estrogen-related receptor alpha (ERRalpha) and gamma (ERRgamma) on the regulation of ERRalpha gene expression." in: Molecular and cellular endocrinology, Vol. 264, Issue 1-2, pp. 128-41, (2007) (PubMed).

Synonyms and alternative names related to ESRRG

estrogen related receptor gamma (ESRRG), estrogen related receptor gamma (esrrg), estrogen-related receptor gamma (Esrrg), estrogen-related receptor gamma a (esrrga), estrogen-related receptor gamma b (esrrgb), estrogen related receptor gamma (Esrrg), DKFZp459J0417, ERR3, err3, errb/g, errbeta/gamma, errg, Errg, ERRgamma, errgamma, ESRRG, esrrg, esrrgl, LOC100219115, mKIAA0832, NR3B3, nr3b3, USH2A

Protein level used designations for ESRRG

  • ERR gamma-2
  • estrogen receptor-related protein 3
  • nuclear receptor subfamily 3 group B member 3
  • estrogen-related receptor gamma
  • Usher syndrome 2A (autosomal recessive, mild)
  • NR3B3
  • NR3B2/3
  • estrogen-related receptor beta/gamma
  • estrogen-related receptor 3
  • estrogen-related receptor gamma-like
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