ERCC1 抗体
(Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009].
recommended
ERCC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
ERCC1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5A2D1 unconjugated
recommended
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Quantity
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Quantity
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Latest Publications for our ERCC1 抗体
: "ERCC1 as predictive biomarker to platinum-based chemotherapy in adrenocortical carcinomas." in: European journal of endocrinology, Vol. 178, Issue 2, pp. 181-188, (2018) (PubMed).: "A novel antibody-based approach to detect the functional ERCC1-202 isoform." in: DNA repair, Vol. 64, pp. 34-44, (2018) (PubMed).
: "Development and Validation of an ERCC1 Immunohistochemistry Assay for Solid Tumors." in: Archives of pathology & laboratory medicine, Vol. 140, Issue 12, pp. 1397-1403, (2016) (PubMed).
: "Aging asymmetry: systematic survey of changes in age-related biomarkers in the annual fish Nothobranchius guentheri." in: Fish physiology and biochemistry, (2016) (PubMed).
: "Classic biphasic pulmonary blastoma with brain and axillary metastases: a case report with molecular analysis and review of literature." in: International journal of clinical and experimental pathology, Vol. 8, Issue 1, pp. 983-8, (2015) (PubMed).
: "Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers." in: PLoS ONE, Vol. 10, Issue 4, pp. e0122046, (2015) (PubMed).
: "The clue of a possible etiology about spontaneous regression of hepatocellular carcinoma: a perspective on pathology." in: OncoTargets and therapy, Vol. 8, pp. 395-400, (2015) (PubMed).
: "Primary urinary bladder adenosquamous carcinoma complicated with lower limb deep venous thromboses: a case report." in: International journal of clinical and experimental pathology, Vol. 7, Issue 12, pp. 9032-7, (2015) (PubMed).
: "A phase 2 cooperative group adjuvant trial using a biomarker-based decision algorithm in patients with stage I non-small cell lung cancer (SWOG-0720, NCT00792701)." in: Cancer, Vol. 120, Issue 15, pp. 2343-51, (2014) (PubMed).
: "Measuring ERCC1 protein expression in cancer specimens: validation of a novel antibody." in: Scientific reports, Vol. 4, pp. 4313, (2014) (PubMed).
Aliases for ERCC1 抗体
ERCC excision repair 1, endonuclease non-catalytic subunit (ERCC1) 抗体excision repair cross-complementing rodent repair deficiency, complementation group 1 (Ercc1) 抗体
ERCC excision repair 1, endonuclease non-catalytic subunit (Ercc1) 抗体
DNA excision repair protein ERCC-1 (CC1G_04546) 抗体
DNA excision repair protein ERCC-1 (CpipJ_CPIJ013903) 抗体
DNA excision repair protein ERCC-1 (PITG_13719) 抗体
ERCC excision repair 1, endonuclease non-catalytic subunit (ercc1) 抗体
nucleotide repair protein (ERCC1) 抗体
excision repair cross-complementation group 1 L homeolog (ercc1.L) 抗体
excision repair cross-complementation group 1 (ercc1) 抗体
COFS4 抗体
Ercc-1 抗体
ercc1 抗体
RAD10 抗体
T12H1.18 抗体
T12H1_18 抗体
UV20 抗体
UVR7 抗体
UV REPAIR DEFICIENT 7 抗体
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