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EPOR 产品

(Erythropoietin Receptor (EPOR))

Categories

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010].

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Featured EPOR Categories

EPOR 抗体

High quality antibodies with extensive validation data.

EPOR ELISA试剂盒

Reliable ELISA kits for a wide range of species.

EPOR 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EPOR 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (6)
Cat. No. ABIN560776
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
  • (4)
Cat. No. ABIN686347
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (5)
Cat. No. ABIN6243002
Quantity 400 μL
Datasheet Datasheet

Recommended EPOR ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6955646
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955647
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1979359
Quantity 96 tests
Datasheet Datasheet

Recommended EPOR 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN5854452
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122817
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352979
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our EPOR Products

Vizcardo-Galindo, León-Velarde, Villafuerte: "High-Altitude Hypoxia Decreases Plasma Erythropoietin Soluble Receptor Concentration in Lowlanders." in: High altitude medicine & biology, Vol. 21, Issue 1, pp. 92-98, (2020) (PubMed).

Tarantini, Valcarcel-Ares, Toth, Yabluchanskiy, Tucsek, Kiss, Hertelendy, Kinter, Ballabh, Süle, Farkas, Baur, Sinclair, Csiszar, Ungvari: "Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice." in: Redox biology, Vol. 24, pp. 101192, (2019) (PubMed).

Chen, Li, Quan, Zhou, Zhao, Zhang, Hu, Hu: "The Effects of Curcumae Longae Radix, Curcuma phaeocaulis Radix and Their Processed Products on Epo/EpoR Pathway and CD62p." in: Frontiers in pharmacology, Vol. 9, pp. 736, (2018) (PubMed).

Villafuerte, Corante, Anza-Ramírez, Figueroa-Mujíca, Vizcardo-Galindo, Mercado, Macarlupú, León-Velarde: "Plasma soluble erythropoietin receptor is decreased during sleep in Andean highlanders with Chronic Mountain Sickness." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 121, Issue 1, pp. 53-8, (2016) (PubMed).

Li, Chen, Shao, Tang, Chen, Chen, Xu: "Oxidative stress induces the decline of brain EPO expression in aging rats." in: Experimental gerontology, Vol. 83, pp. 89-93, (2016) (PubMed).

Zhong, Zhang: "Age-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations." in: Molecular medicine reports, Vol. 15, Issue 1, pp. 228-234, (2016) (PubMed).

Kai-lan, Si: "Pretreatment With Erythropoietin Attenuates Intestinal Ischemia Reperfusion Injury by Further Promoting PI3K/Akt Signaling Activation." in: Transplantation proceedings, Vol. 47, Issue 6, pp. 1639-45, (2016) (PubMed).

Maxwell, Melendez-Rodríguez, Matchett, Aragones, Ben-Califa, Jaekel, Hengst, Lindner, Bernardini, Brockmeier, Fandrey, Grunert, Oster, Mittelman, El-Tanani, Thiersch, Schneider Gasser, Gassmann et al.: "Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation. ..." in: British journal of haematology, Vol. 168, Issue 3, pp. 429-42, (2015) (PubMed).

Hatayama, Ide: "Engineering of erythropoietin receptor for use as an affinity ligand." in: Protein expression and purification, Vol. 111, pp. 1-8, (2015) (PubMed).

Villafuerte, Macarlupú, Anza-Ramírez, Corrales-Melgar, Vizcardo-Galindo, Corante, León-Velarde: "Decreased plasma soluble erythropoietin receptor in high-altitude excessive erythrocytosis and Chronic Mountain Sickness." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 117, Issue 11, pp. 1356-62, (2014) (PubMed).

Synonyms and alternative names related to EPOR

erythropoietin receptor (EPOR), erythropoietin receptor (epor), erythropoietin receptor (Epor), erythropoietin receptor L homeolog (epor.L), EPO-R, EPOR, epor

Protein level used designations for EPOR

  • erythropoietin receptor
  • Erythropoietin receptor
  • type I single-transmembrane cytokine receptor
  • erythropoietin receptor-like
  • EPO-R
  • xlEPOR
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