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Enhancer of Zeste Homolog 2 产品

(Enhancer of Zeste Homolog 2 (EZH2))

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This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011].

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Featured Enhancer of Zeste Homolog 2 Categories

Enhancer of Zeste Homolog 2 抗体

High quality antibodies with extensive validation data.

Enhancer of Zeste Homolog 2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Enhancer of Zeste Homolog 2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Enhancer of Zeste Homolog 2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7436762
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (6)
Cat. No. ABIN5542715
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, FACS, IHC (p)
Validations
  • (1)
  • (6)
Cat. No. ABIN650707
Quantity 400 μL
Datasheet Datasheet

Recommended Enhancer of Zeste Homolog 2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966524
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955581
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1503082
Quantity 96 tests
Datasheet Datasheet

Recommended Enhancer of Zeste Homolog 2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1353283
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353285
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus
Validations
  • (2)
Cat. No. ABIN2669606
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our Enhancer of Zeste Homolog 2 Products

León-González, Jara-Palacios, Abbas, Heredia, Schini-Kerth: "Role of epigenetic regulation on the induction of apoptosis in Jurkat leukemia cells by white grape pomace rich in phenolic compounds." in: Food & function, Vol. 8, Issue 11, pp. 4062-4069, (2018) (PubMed).

Cao, Liu, Yue, Liu, Pei, Gu, Wang, Jia: "Iron chelation inhibits cancer cell growth and modulates global histone methylation status in colorectal cancer." in: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, Vol. 31, Issue 5, pp. 797-805, (2018) (PubMed).

Xie, Wang, Zhuang, Hou, Liu, Wu, Liu, Huang: "Decreased miR-320a promotes invasion and metastasis of tumor budding cells in tongue squamous cell carcinoma." in: Oncotarget, Vol. 7, Issue 40, pp. 65744-65757, (2018) (PubMed).

Pan, Wang, Zhu, Xing, Cui, Li, Yu, Wang, Zhu, Ye, Wu, Wang, Lu: "STAT3 signaling drives EZH2 transcriptional activation and mediates poor prognosis in gastric cancer." in: Molecular cancer, Vol. 15, Issue 1, pp. 79, (2017) (PubMed).

Li, Lin, Yang, Wu, He: "Long noncoding RNA H19 regulates EZH2 expression by interacting with miR-630 and promotes cell invasion in nasopharyngeal carcinoma." in: Biochemical and biophysical research communications, Vol. 473, Issue 4, pp. 913-9, (2016) (PubMed).

Riquelme, Behrens, Lin, Simon, Papadimitrakopoulou, Izzo, Moran, Kalhor, Lee, Minna, Wistuba: "Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations." in: Cancer research, Vol. 76, Issue 3, pp. 675-85, (2016) (PubMed).

Toth, Papp, Brulois, Choi, Gao, Jung: "LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection." in: PLoS pathogens, Vol. 12, Issue 9, pp. e1005878, (2016) (PubMed).

Izzo, Mercogliano, Venturutti, Tkach, Inurrigarro, Schillaci, Cerchietti, Elizalde, Proietti: "Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth." in: Breast cancer research : BCR, Vol. 16, Issue 6, pp. 491, (2015) (PubMed).

Wan, Zhan, Li, Ma, Xu, Liu, Xue, Xie, Fang, Chin, Zhang: "PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression." in: Nucleic acids research, Vol. 43, Issue 7, pp. 3591-604, (2015) (PubMed).

Adelaiye, Ciamporcero, Miles, Sotomayor, Bard, Tsompana, Conroy, Shen, Ramakrishnan, Ku, Orillion, Prey, Fetterly, Buck, Chintala, Bjarnason, Pili: "Sunitinib dose escalation overcomes transient resistance in clear cell renal cell carcinoma and is associated with epigenetic modifications." in: Molecular cancer therapeutics, Vol. 14, Issue 2, pp. 513-22, (2015) (PubMed).

Synonyms and alternative names related to Enhancer of Zeste Homolog 2

enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2), enhancer of zeste 2 polycomb repressive complex 2 subunit (ezh2), enhancer of zeste 2 polycomb repressive complex 2 subunit (Ezh2), enhancer of zeste 2 polycomb repressive complex 2 subunit L homeolog (ezh2.L), enhancer of zeste 2 polycomb repressive complex 2 subunit S homeolog (ezh2.S), ENX-1, enx-1, Enx-1, ENX1, enx1, Enx1h, eya2, EZH1, ezh1, EZH2, ezh2, EZH2b, im:7149338, KMT6, kmt6, KMT6A, mKIAA4065, olezh2, WVS, WVS2, xez, zgc:136376, zgc:152758

Protein level used designations for Enhancer of Zeste Homolog 2

  • histone-lysine N-methyltransferase EZH2
  • lysine N-methyltransferase 6
  • eyes absent homolog 2
  • enhancer of zeste 2
  • enhancer of zeste homolog 2 (Drosophila)
  • Polycomb protein EZH2
  • Enhancer of zeste homolog 2-A
  • Polycomb protein EZH2-A
  • histone-lysine N-methyltransferase EZH2-like
  • enhancer of zeste homolog 2
  • Enhancer of zeste homolog 2-B
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