This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012].
Find EMR2 抗体 for a variety of species such as anti-Human EMR2, anti-Mouse EMR2, anti-Dog EMR2. The species listed below are among those available. Click on a link to go to the corresponding products.
EMR2 抗体 by 应用范围
Find EMR2 抗体 validated for a specific application such as WB, ELISA, IF, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.
EMR2 抗体 by 抗体来源
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EMR2 抗体 by 抗原表位
Find EMR2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
EMR2 抗体 by 克隆形成能力
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EMR2 抗体 by 克隆
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EMR2 抗体 by 标记
Find EMR2 抗体 with a specific conjugate such as PE, Biotin. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Kwakkenbos, Kop, Stacey, Matmati, Gordon, Lin, Hamann: "The EGF-TM7 family: a postgenomic view." in: Immunogenetics, Vol. 55, Issue 10, pp. 655-66, (2004) (PubMed).
Stacey, Chang, Davies, Kwakkenbos, Sanderson, Hamann, Gordon, Lin: "The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans." in: Blood, Vol. 102, Issue 8, pp. 2916-24, (2003) (PubMed).
Kwakkenbos, Chang, Lin, Pouwels, de Jong, van Lier, Gordon, Hamann: "The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells." in: Journal of leukocyte biology, Vol. 71, Issue 5, pp. 854-62, (2002) (PubMed).
Aliases for EMR2 抗体
adhesion G protein-coupled receptor E2 (ADGRE2) 抗体 adhesion G protein-coupled receptor E2 (LOC484898) 抗体 CD312 抗体 EMR2 抗体
