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EIF4B 产品

(Eukaryotic Translation Initiation Factor 4B (EIF4B))
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

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Featured EIF4B Categories

EIF4B 抗体

High quality antibodies with extensive validation data.

EIF4B ELISA试剂盒

Reliable ELISA kits for a wide range of species.

EIF4B 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EIF4B 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (2)
  • (6)
Cat. No. ABIN969517
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, FACS
Validations
  • (6)
Cat. No. ABIN1497978
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
Cat. No. ABIN6140078
Quantity 100 μL
Datasheet Datasheet

Recommended EIF4B ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380298
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended EIF4B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1352593
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7425053
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7425056
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our EIF4B Products

Galan, Lozano, Piñeiro, Martinez-Salas: "G3BP1 interacts directly with the FMDV IRES and negatively regulates translation." in: The FEBS journal, Vol. 284, Issue 19, pp. 3202-3217, (2017) (PubMed).

Cen, Xiong, Song, Mahajan, DuPont, McEachern, DeAngelo, Cortes, Minden, Ebens, Mims, LaRue, Kraft: "The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling." in: Molecular and cellular biology, Vol. 34, Issue 13, pp. 2517-32, (2014) (PubMed).

Meijer, Kong, Lu, Wilczynska, Spriggs, Robinson, Godfrey, Willis, Bushell: "Translational repression and eIF4A2 activity are critical for microRNA-mediated gene regulation." in: Science (New York, N.Y.), Vol. 340, Issue 6128, pp. 82-5, (2013) (PubMed).

Chen, Lin, Chow, Lee: "Proteomic identification of Hsp70 as a new Plk1 substrate in arsenic trioxide-induced mitotically arrested cells." in: Proteomics, Vol. 11, Issue 22, pp. 4331-45, (2011) (PubMed).

Mokas, Mills, Garreau, Fournier, Robert, Arya, Kaufman, Pelletier, Mazroui: "Uncoupling stress granule assembly and translation initiation inhibition." in: Molecular biology of the cell, Vol. 20, Issue 11, pp. 2673-83, (2009) (PubMed).

Shahbazian, Roux, Mieulet, Cohen, Raught, Taunton, Hershey, Blenis, Pende, Sonenberg: "The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity." in: The EMBO journal, Vol. 25, Issue 12, pp. 2781-91, (2006) (PubMed).

Suzuki, Fujisawa, Ando, Niino, Ohsawa, Shimokata, Ohta: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." in: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).

Doepker, Hsu, Saffran, Smiley: "Herpes simplex virus virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4H." in: Journal of virology, Vol. 78, Issue 9, pp. 4684-99, (2004) (PubMed).

Fleming, Ghuman, Yuan, Simpson, Szendröi, Matthews, Curry: "Solution structure and RNA interactions of the RNA recognition motif from eukaryotic translation initiation factor 4B." in: Biochemistry, Vol. 42, Issue 30, pp. 8966-75, (2003) (PubMed).

Gingras, Raught, Sonenberg: "Regulation of translation initiation by FRAP/mTOR." in: Genes & development, Vol. 15, Issue 7, pp. 807-26, (2001) (PubMed).

Synonyms and alternative names related to EIF4B

eukaryotic translation initiation factor 4B (EIF4B), eukaryotic initiation factor 4B (Eif4B), Eukaryotic initiation factor 4B (eIF-4B), eukaryotic translation initiation factor 4B (Eif4b), eukaryotic translation initiation factor 4Bb (eif4bb), eukaryotic translation initiation factor 4B (eif4b), eukaryotic translation initiation factor 4Ba (eif4ba), eukaryotic translation initiation factor 4B S homeolog (eif4b.S), eukaryotic translation initiation factor 4B (LOC100284982), eukaryotic translation initiation factor 4B (LOC100380867), 2310046H11Rik, AL024095, C85189, CG10837, Dm-eIF4B, Dmel\\CG10837, EIF-4B, eIF-4b, eIF-4B-L, eIF-4B-S, Eif4a2, Eif4B, eIF4B, eIf4b, eif4b, eIF4B-L, eIF4B-S, fb15c09, MGC89384, PRO1843, wu:fb15c09, zgc:101532

Protein level used designations for EIF4B

  • eukaryotic initiation factor 4B
  • CG10837-PA
  • CG10837-PB
  • CG10837-PE
  • CG10837-PF
  • eIF-4B-PA
  • eIF-4B-PB
  • eIF-4B-PE
  • eIF-4B-PF
  • eukaryotic translation initiation factor 4B
  • eIF-4B
  • hypothetical protein
  • Eukaryotic translation initiation factor 4B
  • LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4B
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