EIF4A1 产品
(Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))
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ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
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Cat. No.
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Latest Publications for our EIF4A1 Products
: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." in: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).: "Inclusion bodies of human parainfluenza virus type 3 inhibit antiviral stress granule formation by shielding viral RNAs." in: PLoS pathogens, Vol. 14, Issue 3, pp. e1006948, (2018) (PubMed).
: "Dynamic Interaction of Eukaryotic Initiation Factor 4G1 (eIF4G1) with eIF4E and eIF1 Underlies Scanning-Dependent and -Independent Translation." in: Molecular and cellular biology, Vol. 38, Issue 18, (2018) (PubMed).
: "Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress." in: eLife, Vol. 6, (2017) (PubMed).
: "PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 9, pp. 3274-9, (2008) (PubMed).
: "Anti-inflammatory lipid mediator 15d-PGJ2 inhibits translation through inactivation of eIF4A." in: The EMBO journal, Vol. 26, Issue 24, pp. 5020-32, (2007) (PubMed).
Synonyms and alternative names related to EIF4A1
eukaryotic translation initiation factor 4A1 (EIF4A1), eukaryotic translation initiation factor 4A1 (Eif4a1), eukaryotic translation initiation factor 4A1 L homeolog (eif4a1.L), eukaryotic translation initiation factor 4A1 (eif4a1), eukaryotic initiation factor 4A-I (LOC695050), eukaryotic translation initiation factor 4A1A (eif4a1a), BM-010, DDX2A, Ddx2a, ddx2a, EIF-4A, eif-4a, eIF-4A-I, Eif4, EIF4A, eif4a, eIF4A-I, eif4a1, fb49a04, im:7143023, wu:fb20a10, wu:fb49a04, wu:fc76a02, wu:fc96c01, wu:fd15g03Protein level used designations for EIF4A1
- ATP-dependent RNA helicase eIF4A-1
- eukaryotic initiation factor 4A-I
- eukaryotic initiation factor 4AI
- eukaryotic translation initiation factor 4A
- eIF-4A-I
- eIF4A-I
- initiation factor eIF-4A long form
- translation initiation factor eIF4A I
- eukaryotic translation initiation factor 4A1
- eukaryotic translation initiation factor 4A-like
- eukaryotic initiation factor 4A-I-like
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