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EIF3L 产品

(Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))

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Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (By similarity).

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Featured EIF3L Categories

EIF3L 抗体

High quality antibodies with extensive validation data.

EIF3L 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EIF3L 抗体

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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
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  • (3)
Cat. No. ABIN7264988
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6262447
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN6140074
Quantity 100 μL
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Recommended EIF3L ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228851
Quantity 96 tests
Datasheet Datasheet

Recommended EIF3L 蛋白

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Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352582
Quantity 10 μg
Datasheet Datasheet
Reactivity Aspergillus clavatus
Source Yeast
Validations
Cat. No. ABIN1458058
Quantity 1 mg
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Latest Publications for our EIF3L Products

Zhou, Sandercock, Fraser, Ridlova, Stephens, Schenauer, Yokoi-Fong, Barsky, Leary, Hershey, Doudna, Robinson: "Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18139-44, (2008) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Masutani, Sonenberg, Yokoyama, Imataka: "Reconstitution reveals the functional core of mammalian eIF3." in: The EMBO journal, Vol. 26, Issue 14, pp. 3373-83, (2007) (PubMed).

Damoc, Fraser, Zhou, Videler, Mayeur, Hershey, Doudna, Robinson, Leary: "Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 7, pp. 1135-46, (2007) (PubMed).

Synonyms and alternative names related to EIF3L

eukaryotic translation initiation factor 3, subunit 6 interacting protein (eif3s6ip), eukaryotic translation initiation factor 3 subunit L (EIF3L), eukaryotic translation initiation factor 3, subunit L (Eif3l), eukaryotic translation initiation factor 3 subunit L L homeolog (eif3l.L), 0610011H21Rik, D15N1e, EIF3EIP, Eif3eip, eif3eip, Eif3ip, EIF3S6IP, Eif3s6ip, eif3s6ip, EIF3S11, HSP-66Y, HSPC021, HSPC025, MSTP005, PAF67, wu:fb66c05, zgc:64147

Protein level used designations for EIF3L

  • eIF3l
  • eukaryotic translation initiation factor 3 subunit 6-interacting protein
  • eukaryotic translation initiation factor 3 subunit E-interacting protein
  • eukaryotic translation initiation factor 3 subunit L
  • eIEF associated protein HSPC021
  • 66 kDa tyrosine-rich heat shock protein
  • 67 kDa polymerase-associated factor
  • eukaryotic translation initiation factor 3, subunit 6 interacting protein
  • eukaryotic translation initiation factor 3, subunit E interacting protein
  • Eukaryotic translation initiation factor 3 subunit 6-interacting protein
  • Eukaryotic translation initiation factor 3 subunit E-interacting protein
  • eukaryotic translation initiation factor 3 subunit 6 interacting protein
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