EIF3E 抗体
(Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins. {ECO:0000255|HAMAP-Rule:MF_03004}.
recommended
EIF3E 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
recommended
recommended
EIF3E 抗体 by Grade
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EIF3E 抗体 by 应用范围
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EIF3E 抗体 by 克隆形成能力
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EIF3E 抗体 by 克隆
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EIF3E 抗体 by 标记
Find EIF3E 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular EIF3E 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN2783260
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
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Cat. No.
ABIN561508
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7152153
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC, IHC (p)
Validations
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Cat. No.
ABIN6747119
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Human, Monkey, Mouse, Rat
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN349583
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Zebrafish (Danio rerio)
Application
WB
Validations
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Cat. No.
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Quantity
400 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IF
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Cat. No.
ABIN7261403
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN571273
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
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Cat. No.
ABIN6741024
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
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Cat. No.
ABIN6140059
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IC
Validations
- (2)
Cat. No.
ABIN7306290
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
Cat. No.
ABIN6989667
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
Cat. No.
ABIN6389612
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF
Validations
Cat. No.
ABIN7113947
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our EIF3E 抗体
: "An oncogenic role of eIF3e/INT6 in human breast cancer." in: Oncogene, Vol. 29, Issue 28, pp. 4080-9, (2010) (PubMed).: "Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18139-44, (2008) (PubMed).
: "Human INT6/eIF3e is required for nonsense-mediated mRNA decay." in: EMBO reports, Vol. 8, Issue 6, pp. 596-602, (2007) (PubMed).
: "Reconstitution reveals the functional core of mammalian eIF3." in: The EMBO journal, Vol. 26, Issue 14, pp. 3373-83, (2007) (PubMed).
: "Mid-region parathyroid hormone-related protein (PTHrP) and gene expression of MDA-MB231 breast cancer cells." in: Biological chemistry, Vol. 388, Issue 5, pp. 457-65, (2007) (PubMed).
: "A new common integration site, Int7, for the mouse mammary tumor virus in mouse mammary tumors identifies a gene whose product has furin-like and thrombospondin-like sequences." in: Journal of virology, Vol. 79, Issue 15, pp. 10093-6, (2005) (PubMed).
: "Int6 expression can predict survival in early-stage non-small cell lung cancer patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 9, pp. 3198-204, (2005) (PubMed).
: "Fission yeast Int6 is not essential for global translation initiation, but deletion of int6(+) causes hypersensitivity to caffeine and affects spore formation." in: Molecular biology of the cell, Vol. 11, Issue 11, pp. 4005-18, (2001) (PubMed).
Aliases for EIF3E 抗体
eukaryotic translation initiation factor 3 subunit E (EIF3E) 抗体eukaryotic translation initiation factor 3, subunit E (Eif3e) 抗体
eukaryotic translation initiation factor 3 subunit E (eif3e) 抗体
eukaryotic translation initiation factor 3 subunit E L homeolog (eif3e.L) 抗体
eukaryotic translation initiation factor 3 subunit 6 (LOC692936) 抗体
eukaryotic translation initiation factor 3 subunit E S homeolog (eif3e.S) 抗体
eukaryotic translation initiation factor 3, subunit E, a (eif3ea) 抗体
Eukaryotic translation initiation factor 3 subunit E (eif-3.E) 抗体
eukaryotic translation initiation factor 3, subunit E, b (eif3eb) 抗体
eukaryotic translation initiation factor 3 subunit E (Eif3e) 抗体
eukaryotic translation initiation factor 3 subunit E (LOC108348260) 抗体
eukaryotic translation initiation factor 3 subunit E (int6) 抗体
48kDa 抗体
eIF3-p46 抗体
EIF3-P48 抗体
eIF3-p48 抗体
eif3-p48 抗体
eIF3-S6 抗体
eIF3e 抗体
EIF3S6 抗体
Eif3s6 抗体
eif3s6 抗体
eif3s6-A 抗体
eif3s6-B 抗体
eif3s6b 抗体
EIF3SE 抗体
im:7147439 抗体
INT6 抗体
Int6 抗体
QtsA-18056 抗体
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