EIF3A 产品
(Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
Categories
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
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Featured EIF3A Categories
EIF3A 抗体
High quality antibodies with extensive validation data.
EIF3A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
EIF3A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended EIF3A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN7254935
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (2)
Cat. No.
ABIN1679692
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7152145
Quantity
100 μg
Datasheet
Datasheet
Recommended EIF3A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966611
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1132475
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1132476
Quantity
96 tests
Datasheet
Datasheet
Recommended EIF3A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352552
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our EIF3A Products
: "A threonyl-tRNA synthetase-mediated translation initiation machinery." in: Nature communications, Vol. 10, Issue 1, pp. 1357, (2019) (PubMed).: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." in: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).
: "ABCE1 is essential for S phase progression in human cells." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 9, pp. 1234-47, (2016) (PubMed).
: "eIF3 targets cell-proliferation messenger RNAs for translational activation or repression." in: Nature, Vol. 522, Issue 7554, pp. 111-4, (2015) (PubMed).
: "EJC core component MLN51 interacts with eIF3 and activates translation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 15, pp. 5903-8, (2013) (PubMed).
: "Interferon-dependent engagement of eukaryotic initiation factor 4B via S6 kinase (S6K)- and ribosomal protein S6K-mediated signals." in: Molecular and cellular biology, Vol. 29, Issue 10, pp. 2865-75, (2009) (PubMed).
Synonyms and alternative names related to EIF3A
eukaryotic translation initiation factor 3 subunit A (EIF3A), eukaryotic translation initiation factor 3, subunit A (Eif3a), eukaryotic translation initiation factor 3 subunit A S homeolog (eif3a.S), translation initiation factor eIF3a (tif32), eukaryotic translation initiation factor 3 subunit A (Eif3a), A830012B05Rik, Csma, EIF3, Eif3, eIF3 p110, eIF3-p170, eIF3-theta, eIF3a, EIF3S10, Eif3s10, eif3s10, EIF6, mKIAA0139, P167, p180, p185, TIF32, ZH12Protein level used designations for EIF3A
- EIF3, p180 subunit
- centrosomin homolog
- cytoplasmic protein p167
- eIF-3-theta
- eIF3 p167
- eIF3 p180
- eIF3 p185
- eukaryotic translation initiation factor 3 subunit 10
- eukaryotic translation initiation factor 3 subunit A
- eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD)
- eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD)
- eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa
- eukaryotic translation initiation factor 3, subunit 10, 170kD
- eukaryotic translation initiation factor 6
- EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN)
- centrosomin
- eukaryotic translation initiation factor 3, subunit 10 (theta)
- p162
- Eukaryotic translation initiation factor 3 subunit 10
- Eukaryotic translation initiation factor 3 110 kDa subunit
- Translation initiation factor eIF3, p110 subunit
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