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EIF2B3 产品

(Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))

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The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].

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Featured EIF2B3 Categories

EIF2B3 抗体

High quality antibodies with extensive validation data.

EIF2B3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EIF2B3 抗体

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Cat. No. ABIN522375
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Cat. No. ABIN7186610
Quantity 100 μg
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Recommended EIF2B3 ELISA试剂盒

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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6216791
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Recommended EIF2B3 蛋白

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Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN2720068
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Latest Publications for our EIF2B3 Products

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

van der Knaap, Leegwater, Könst, Visser, Naidu, Oudejans, Schutgens, Pronk: "Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter." in: Annals of neurology, Vol. 51, Issue 2, pp. 264-70, (2002) (PubMed).

Gomez, Pavitt et al.: "Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation ..." in: Molecular and cellular biology, Vol. 20, Issue 11, pp. 3965-76, (2000) (PubMed).

Kruger, Beger, Li, Welch, Tritz, Leavitt, Barber, Wong-Staal: "Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 15, pp. 8566-71, (2000) (PubMed).

Synonyms and alternative names related to EIF2B3

eukaryotic translation initiation factor 2B subunit gamma L homeolog (eif2b3.L), eukaryotic translation initiation factor 2B, subunit 3 gamma (eif2b3), eukaryotic translation initiation factor 2B subunit gamma (EIF2B3), eukaryotic translation initiation factor 2B subunit gamma (eif2b3), eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa (Eif2b3), eukaryotic translation initiation factor 2B subunit gamma (Eif2b3), eukaryotic translation initiation factor 2B, subunit 3 (Eif2b3), 1190002P15Rik, EIF-2B, EIF2Bgamma, zgc:56473

Protein level used designations for EIF2B3

  • eukaryotic translation initiation factor 2B, subunit 3 gamma
  • translation initiation factor eIF-2B subunit gamma
  • eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
  • Translation initiation factor eIF-2B subunit gamma-like protein
  • eIF2B-gamma protein
  • translation initiation factor eIF-2B subunit gamma-like
  • eIF-2B GDP-GTP exchange factor subunit gamma
  • eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD)
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