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EGLN1 抗体

(Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq, Nov 2009].
EGLN1 抗体  (AA 1-426) EGLN1 抗体  (AA 1-426) EGLN1 抗体 (AA 1-426) (ABIN7266909)

KO Validated EGLN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

EGLN1 抗体  (AA 42-140) EGLN1 抗体  (AA 42-140) EGLN1 抗体 (AA 42-140) (ABIN702640)

EGLN1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

EGLN1 抗体  (AA 301-426) EGLN1 抗体  (AA 301-426) EGLN1 抗体 (AA 301-426) (ABIN7151443)

EGLN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

EGLN1 抗体 by Grade

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EGLN1 抗体 by 适用

Find EGLN1 抗体 for a variety of species such as anti-Human EGLN1, anti-Mouse EGLN1, anti-Rat EGLN1. The species listed below are among those available. Click on a link to go to the corresponding products.

EGLN1 抗体 by 应用范围

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EGLN1 抗体 by 抗原表位

Find EGLN1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

EGLN1 抗体 by 克隆形成能力

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EGLN1 抗体 by 克隆

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EGLN1 抗体 by 标记

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Popular EGLN1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN7266909
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN702640
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7151443
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN565755
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6261464
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7305930
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7151442
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, StM
Validations
  • (1)
Cat. No. ABIN6940360
Quantity 100 μg
Datasheet Datasheet
Reactivity Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN202496
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP
Validations
  • (2)
Cat. No. ABIN363514
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, IF (cc), IHC (p)
Validations
Cat. No. ABIN6989779
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN702642
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN2805290
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN5008738
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN5008739
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our EGLN1 抗体

Liu, Zhang, Guo, Chen, Lei, Ze, Dong, Dai, Gao, Song, Ecker, Yang, Feltcher, Peng, Feng, Chen, Lee, Kerestes, Niu, Kumar, Xu, Zhang, Wei, Martin, Liu, Mills, Lu, Guo, Sun, Zhang, Weeraratna, Herlyn et al.: "Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis. ..." in: Nature communications, Vol. 9, Issue 1, pp. 5426, (2019) (PubMed).

Kurelac, Iommarini, Vatrinet, Amato, De Luise, Leone, Girolimetti, Umesh Ganesh, Bridgeman, Ombrato, Columbaro, Ragazzi, Gibellini, Sollazzo, Feichtinger, Vidali, Baldassarre, Foriel, Vidone et al.: "Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses. ..." in: Nature communications, Vol. 10, Issue 1, pp. 903, (2019) (PubMed).

Chowdhury, Alrefai, Landero Figueroa, Candor, Porollo, Fecher, Divanovic, Deepe, Subramanian Vignesh: "Metallothionein 3 Controls the Phenotype and Metabolic Programming of Alternatively Activated Macrophages." in: Cell reports, Vol. 27, Issue 13, pp. 3873-3886.e7, (2019) (PubMed).

Dabral, Muecke, Valasarajan, Schmoranzer, Wietelmann, Semenza, Meister, Muley, Seeger-Nukpezah, Samakovlis, Weissmann, Grimminger, Seeger, Savai, Pullamsetti: "A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension." in: Nature communications, Vol. 10, Issue 1, pp. 2130, (2019) (PubMed).

Yamamoto, Hester, Macklin, Kawai, Uchiyama, Biggs, Bishop, Bull, Cheng, Cawthorne, Coleman, Crockford, Davies, Dow, Goldin, Kranc, Kudo, Lawson, McAuliffe, Milward, Scudamore, Soilleux, Issa et al.: "Systemic silencing of PHD2 causes reversible immune regulatory dysfunction. ..." in: The Journal of clinical investigation, Vol. 130, pp. 3640-3656, (2019) (PubMed).

Sim, Cowburn, Palazon, Madhu, Tyrakis, Macías, Bargiela, Pietsch, Gralla, Evans, Kittipassorn, Chey, Branco, Rundqvist, Peet, Johnson: "The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia." in: Cell metabolism, Vol. 27, Issue 4, pp. 898-913.e7, (2018) (PubMed).

Akat, Fıçıcılar, Durak, Tuncay, Dursun, Topal Çelikkan, Sabuncuoğlu, Turan, Baştuğ: "Intermittent hypoxia induces beneficial cardiovascular remodeling in left ventricular function of type 1 diabetic rat." in: Anatolian journal of cardiology, Vol. 19, Issue 4, pp. 259-266, (2018) (PubMed).

Deygas, Gadet, Gillet, Rimokh, Gonzalo, Mikaelian: "Redox regulation of EGFR steers migration of hypoxic mammary cells towards oxygen." in: Nature communications, Vol. 9, Issue 1, pp. 4545, (2018) (PubMed).

Miles, Burr, Grice, Nathan: "The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1α prolyl hydroxylation by regulating cellular iron levels." in: eLife, Vol. 6, (2017) (PubMed).

Wang, Zeng, Chen, Zhou, Xie, He, Tao, Tuo, Deng, Liao, Chen: "Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice." in: Journal of cellular and molecular medicine, (2017) (PubMed).

Aliases for EGLN1 抗体

egl nine homolog 1 (C. elegans) (EGLN1) 抗体
egl-9 family hypoxia inducible factor 1 (EGLN1) 抗体
egl-9 family hypoxia-inducible factor 1 S homeolog (egln1.S) 抗体
egl-9 family hypoxia-inducible factor 1b (egln1b) 抗体
egl-9 family hypoxia-inducible factor 1 (Egln1) 抗体
AI503754 抗体
C1orf12 抗体
ECYT3 抗体
EGLN1 抗体
egln2 抗体
Hif-p4h-2 抗体
HIF-PH2 抗体
HIFPH2 抗体
HPH-2 抗体
HPH2 抗体
ORF13 抗体
PHD-2 抗体
phd2 抗体
Phd2 抗体
PHD2 抗体
SM-20 抗体
SM20 抗体
zgc:92314 抗体
ZMYND6 抗体
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